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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GSPT1
Full Name:
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A
Alias:
ERF3a; ETF3A; G1 to S phase transition protein 1; G1 to S phase transition protein 1 homologue; GST1; GST1-HS; GTP-binding protein
Type:
Intracellular protein
Mass (Da):
55756
Number AA:
499
UniProt ID:
P15170
International Prot ID:
IPI00218829
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0003924
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0000082
GO:0000184
GO:0006479
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T13
P
I
V
E
N
G
E
T
E
M
S
P
E
E
S
Site 2
S16
E
N
G
E
T
E
M
S
P
E
E
S
W
E
H
Site 3
S20
T
E
M
S
P
E
E
S
W
E
H
K
E
E
I
Site 4
S36
E
A
E
P
G
G
G
S
L
G
D
G
R
P
P
Site 5
S46
D
G
R
P
P
E
E
S
A
H
E
M
M
E
E
Site 6
S62
E
E
I
P
K
P
K
S
V
V
A
P
P
G
A
Site 7
S88
G
H
V
D
A
G
K
S
T
I
G
G
Q
I
M
Site 8
T89
H
V
D
A
G
K
S
T
I
G
G
Q
I
M
Y
Site 9
T98
G
G
Q
I
M
Y
L
T
G
M
V
D
K
R
T
Site 10
T105
T
G
M
V
D
K
R
T
L
E
K
Y
E
R
E
Site 11
Y109
D
K
R
T
L
E
K
Y
E
R
E
A
K
E
K
Site 12
T120
A
K
E
K
N
R
E
T
W
Y
L
S
W
A
L
Site 13
Y122
E
K
N
R
E
T
W
Y
L
S
W
A
L
D
T
Site 14
T139
E
E
R
D
K
G
K
T
V
E
V
G
R
A
Y
Site 15
Y146
T
V
E
V
G
R
A
Y
F
E
T
E
K
K
H
Site 16
T149
V
G
R
A
Y
F
E
T
E
K
K
H
F
T
I
Site 17
S164
L
D
A
P
G
H
K
S
F
V
P
N
M
I
G
Site 18
T226
I
N
K
M
D
D
P
T
V
N
W
S
N
E
R
Site 19
Y234
V
N
W
S
N
E
R
Y
E
E
C
K
E
K
L
Site 20
Y310
R
L
P
I
V
D
K
Y
K
D
M
G
T
V
V
Site 21
T315
D
K
Y
K
D
M
G
T
V
V
L
G
K
L
E
Site 22
S325
L
G
K
L
E
S
G
S
I
C
K
G
Q
Q
L
Site 23
T353
I
L
S
D
D
V
E
T
D
T
V
A
P
G
E
Site 24
T355
S
D
D
V
E
T
D
T
V
A
P
G
E
N
L
Site 25
S389
D
P
N
N
L
C
H
S
G
R
T
F
D
A
Q
Site 26
S436
I
C
L
V
D
K
K
S
G
E
K
S
K
T
R
Site 27
S440
D
K
K
S
G
E
K
S
K
T
R
P
R
F
V
Site 28
T442
K
S
G
E
K
S
K
T
R
P
R
F
V
K
Q
Site 29
T478
F
P
Q
M
G
R
F
T
L
R
D
E
G
K
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation