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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GNS
Full Name:
N-acetylglucosamine-6-sulfatase
Alias:
Glucosamine-6-sulfatase
Type:
Mass (Da):
62082
Number AA:
552
UniProt ID:
P15586
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
P
G
R
L
R
R
G
S
P
R
H
L
P
S
C
Site 2
T65
D
E
V
L
G
G
M
T
P
L
K
K
T
K
A
Site 3
T100
P
S
R
A
S
I
L
T
G
K
Y
P
H
N
H
Site 4
Y103
A
S
I
L
T
G
K
Y
P
H
N
H
H
V
V
Site 5
S119
N
T
L
E
G
N
C
S
S
K
S
W
Q
K
I
Site 6
S120
T
L
E
G
N
C
S
S
K
S
W
Q
K
I
Q
Site 7
S122
E
G
N
C
S
S
K
S
W
Q
K
I
Q
E
P
Site 8
T131
Q
K
I
Q
E
P
N
T
F
P
A
I
L
R
S
Site 9
Y150
Q
T
F
F
A
G
K
Y
L
N
E
Y
G
A
P
Site 10
Y154
A
G
K
Y
L
N
E
Y
G
A
P
D
A
G
G
Site 11
Y181
A
L
E
K
N
S
K
Y
Y
N
Y
T
L
S
I
Site 12
T185
N
S
K
Y
Y
N
Y
T
L
S
I
N
G
K
A
Site 13
S187
K
Y
Y
N
Y
T
L
S
I
N
G
K
A
R
K
Site 14
S200
R
K
H
G
E
N
Y
S
V
D
Y
L
T
D
V
Site 15
Y203
G
E
N
Y
S
V
D
Y
L
T
D
V
L
A
N
Site 16
Y218
V
S
L
D
F
L
D
Y
K
S
N
F
E
P
F
Site 17
S236
I
A
T
P
A
P
H
S
P
W
T
A
A
P
Q
Site 18
T239
P
A
P
H
S
P
W
T
A
A
P
Q
Y
Q
K
Site 19
Y244
P
W
T
A
A
P
Q
Y
Q
K
A
F
Q
N
V
Site 20
T275
W
L
I
R
Q
A
K
T
P
M
T
N
S
S
I
Site 21
T278
R
Q
A
K
T
P
M
T
N
S
S
I
Q
F
L
Site 22
S280
A
K
T
P
M
T
N
S
S
I
Q
F
L
D
N
Site 23
T295
A
F
R
K
R
W
Q
T
L
L
S
V
D
D
L
Site 24
S298
K
R
W
Q
T
L
L
S
V
D
D
L
V
E
K
Site 25
Y320
T
G
E
L
N
N
T
Y
I
F
Y
T
S
D
N
Site 26
Y323
L
N
N
T
Y
I
F
Y
T
S
D
N
G
Y
H
Site 27
Y329
F
Y
T
S
D
N
G
Y
H
T
G
Q
F
S
L
Site 28
T331
T
S
D
N
G
Y
H
T
G
Q
F
S
L
P
I
Site 29
S335
G
Y
H
T
G
Q
F
S
L
P
I
D
K
R
Q
Site 30
Y344
P
I
D
K
R
Q
L
Y
E
F
D
I
K
V
P
Site 31
Y384
T
I
L
D
I
A
G
Y
D
L
N
K
T
Q
M
Site 32
T389
A
G
Y
D
L
N
K
T
Q
M
D
G
M
S
L
Site 33
S395
K
T
Q
M
D
G
M
S
L
L
P
I
L
R
G
Site 34
S404
L
P
I
L
R
G
A
S
N
L
T
W
R
S
D
Site 35
T407
L
R
G
A
S
N
L
T
W
R
S
D
V
L
V
Site 36
S410
A
S
N
L
T
W
R
S
D
V
L
V
E
Y
Q
Site 37
Y416
R
S
D
V
L
V
E
Y
Q
G
E
G
R
N
V
Site 38
T424
Q
G
E
G
R
N
V
T
D
P
T
C
P
S
L
Site 39
T427
G
R
N
V
T
D
P
T
C
P
S
L
S
P
G
Site 40
S430
V
T
D
P
T
C
P
S
L
S
P
G
V
S
Q
Site 41
S432
D
P
T
C
P
S
L
S
P
G
V
S
Q
C
F
Site 42
Y452
E
D
A
Y
N
N
T
Y
A
C
V
R
T
M
S
Site 43
Y466
S
A
L
W
N
L
Q
Y
C
E
F
D
D
Q
E
Site 44
T489
T
A
D
P
D
Q
I
T
N
I
A
K
T
I
D
Site 45
Y505
E
L
L
G
K
M
N
Y
R
L
M
M
L
Q
S
Site 46
S514
L
M
M
L
Q
S
C
S
G
P
T
C
R
T
P
Site 47
T520
C
S
G
P
T
C
R
T
P
G
V
F
D
P
G
Site 48
Y528
P
G
V
F
D
P
G
Y
R
F
D
P
R
L
M
Site 49
S537
F
D
P
R
L
M
F
S
N
R
G
S
V
R
T
Site 50
S541
L
M
F
S
N
R
G
S
V
R
T
R
R
F
S
Site 51
T544
S
N
R
G
S
V
R
T
R
R
F
S
K
H
L
Site 52
S548
S
V
R
T
R
R
F
S
K
H
L
L
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation