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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF250
Full Name:
Zinc finger protein 250
Alias:
Zinc finger protein 647
Type:
Mass (Da):
63468
Number AA:
560
UniProt ID:
P15622
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
P
A
G
P
Q
P
L
S
F
Q
A
K
L
T
F
Site 2
S32
E
D
V
A
V
L
L
S
Q
D
E
W
D
R
L
Site 3
Y47
C
P
A
Q
R
G
L
Y
R
N
V
M
M
E
T
Site 4
S60
E
T
Y
G
N
V
V
S
L
G
L
P
G
S
K
Site 5
S72
G
S
K
P
D
I
I
S
Q
L
E
R
G
E
D
Site 6
S91
D
R
K
G
A
K
K
S
Q
G
L
W
S
D
Y
Site 7
Y98
S
Q
G
L
W
S
D
Y
S
D
N
L
K
Y
D
Site 8
Y104
D
Y
S
D
N
L
K
Y
D
H
T
T
A
C
T
Site 9
T107
D
N
L
K
Y
D
H
T
T
A
C
T
Q
Q
D
Site 10
T111
Y
D
H
T
T
A
C
T
Q
Q
D
S
L
S
C
Site 11
S128
E
C
E
T
K
G
E
S
Q
N
T
D
L
S
P
Site 12
T131
T
K
G
E
S
Q
N
T
D
L
S
P
K
P
L
Site 13
S134
E
S
Q
N
T
D
L
S
P
K
P
L
I
S
E
Site 14
T149
Q
T
V
I
L
G
K
T
P
L
G
R
I
D
Q
Site 15
T161
I
D
Q
E
N
N
E
T
K
Q
S
F
C
L
S
Site 16
S164
E
N
N
E
T
K
Q
S
F
C
L
S
P
N
S
Site 17
S168
T
K
Q
S
F
C
L
S
P
N
S
V
D
H
R
Site 18
S171
S
F
C
L
S
P
N
S
V
D
H
R
E
V
Q
Site 19
S181
H
R
E
V
Q
V
L
S
Q
S
M
P
L
T
P
Site 20
S183
E
V
Q
V
L
S
Q
S
M
P
L
T
P
H
Q
Site 21
T187
L
S
Q
S
M
P
L
T
P
H
Q
A
V
P
S
Site 22
Y199
V
P
S
G
E
R
P
Y
M
C
V
E
C
G
K
Site 23
S212
G
K
C
F
G
R
S
S
H
L
L
Q
H
Q
R
Site 24
T222
L
Q
H
Q
R
I
H
T
G
E
K
P
Y
V
C
Site 25
Y227
I
H
T
G
E
K
P
Y
V
C
S
V
C
G
K
Site 26
S230
G
E
K
P
Y
V
C
S
V
C
G
K
A
F
S
Site 27
S237
S
V
C
G
K
A
F
S
Q
S
S
V
L
S
K
Site 28
S239
C
G
K
A
F
S
Q
S
S
V
L
S
K
H
R
Site 29
S240
G
K
A
F
S
Q
S
S
V
L
S
K
H
R
R
Site 30
S243
F
S
Q
S
S
V
L
S
K
H
R
R
I
H
T
Site 31
T250
S
K
H
R
R
I
H
T
G
E
K
P
Y
E
C
Site 32
Y255
I
H
T
G
E
K
P
Y
E
C
N
E
C
G
K
Site 33
S267
C
G
K
A
F
R
V
S
S
D
L
A
Q
H
H
Site 34
S268
G
K
A
F
R
V
S
S
D
L
A
Q
H
H
K
Site 35
T306
I
Q
H
Q
R
I
H
T
G
E
R
P
Y
V
C
Site 36
Y311
I
H
T
G
E
R
P
Y
V
C
P
L
C
G
K
Site 37
S323
C
G
K
A
F
N
H
S
T
V
L
R
S
H
Q
Site 38
T324
G
K
A
F
N
H
S
T
V
L
R
S
H
Q
R
Site 39
T334
R
S
H
Q
R
V
H
T
G
E
K
P
H
R
C
Site 40
T347
R
C
N
E
C
G
K
T
F
S
V
K
R
T
L
Site 41
S349
N
E
C
G
K
T
F
S
V
K
R
T
L
L
Q
Site 42
T362
L
Q
H
Q
R
I
H
T
G
E
K
P
Y
T
C
Site 43
Y367
I
H
T
G
E
K
P
Y
T
C
S
E
C
G
K
Site 44
T368
H
T
G
E
K
P
Y
T
C
S
E
C
G
K
A
Site 45
S370
G
E
K
P
Y
T
C
S
E
C
G
K
A
F
S
Site 46
S377
S
E
C
G
K
A
F
S
D
R
S
V
L
I
Q
Site 47
S380
G
K
A
F
S
D
R
S
V
L
I
Q
H
H
N
Site 48
T390
I
Q
H
H
N
V
H
T
G
E
K
P
Y
E
C
Site 49
Y395
V
H
T
G
E
K
P
Y
E
C
S
E
C
G
K
Site 50
S398
G
E
K
P
Y
E
C
S
E
C
G
K
T
F
S
Site 51
T403
E
C
S
E
C
G
K
T
F
S
H
R
S
T
L
Site 52
S405
S
E
C
G
K
T
F
S
H
R
S
T
L
M
N
Site 53
S408
G
K
T
F
S
H
R
S
T
L
M
N
H
E
R
Site 54
T409
K
T
F
S
H
R
S
T
L
M
N
H
E
R
I
Site 55
T418
M
N
H
E
R
I
H
T
E
E
K
P
Y
A
C
Site 56
Y423
I
H
T
E
E
K
P
Y
A
C
Y
E
C
G
K
Site 57
Y426
E
E
K
P
Y
A
C
Y
E
C
G
K
A
F
V
Site 58
T446
I
Q
H
Q
R
V
H
T
G
E
K
P
Y
V
C
Site 59
Y451
V
H
T
G
E
K
P
Y
V
C
G
E
C
G
H
Site 60
S461
G
E
C
G
H
A
F
S
A
R
R
S
L
I
Q
Site 61
S465
H
A
F
S
A
R
R
S
L
I
Q
H
E
R
I
Site 62
T474
I
Q
H
E
R
I
H
T
G
E
K
P
F
Q
C
Site 63
T500
T
L
I
V
H
L
R
T
H
T
G
E
K
P
Y
Site 64
T502
I
V
H
L
R
T
H
T
G
E
K
P
Y
E
C
Site 65
Y507
T
H
T
G
E
K
P
Y
E
C
N
S
C
G
K
Site 66
S511
E
K
P
Y
E
C
N
S
C
G
K
A
F
S
Q
Site 67
S517
N
S
C
G
K
A
F
S
Q
Y
S
V
L
I
Q
Site 68
Y519
C
G
K
A
F
S
Q
Y
S
V
L
I
Q
H
Q
Site 69
S520
G
K
A
F
S
Q
Y
S
V
L
I
Q
H
Q
R
Site 70
T530
I
Q
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 71
Y535
I
H
T
G
E
K
P
Y
E
C
G
E
C
G
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation