PhosphoNET

           
Protein Info 
   
Short Name:  TCF4
Full Name:  Transcription factor 4
Alias:  BHLHb19; Immunoglobulin transcription factor 2; ITF2; ITF-2; SEF2; SEF-2; SEF2-1B; SL3-3 enhancer factor 2; TCF-4
Type:  Transcription protein
Mass (Da):  71308
Number AA:  667
UniProt ID:  P15884
International Prot ID:  IPI00221260
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634     Uniprot OncoNet
Molecular Function:  GO:0046982  GO:0003700  GO:0003702 PhosphoSite+ KinaseNET
Biological Process:  GO:0045893  GO:0006350   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S17LGTDKELSDLLDFSA
Site 2S27LDFSAMFSPPVSSGK
Site 3S31AMFSPPVSSGKNGPT
Site 4S32MFSPPVSSGKNGPTS
Site 5T38SSGKNGPTSLASGHF
Site 6S39SGKNGPTSLASGHFT
Site 7S42NGPTSLASGHFTGSN
Site 8T46SLASGHFTGSNVEDR
Site 9S48ASGHFTGSNVEDRSS
Site 10S54GSNVEDRSSSGSWGN
Site 11S55SNVEDRSSSGSWGNG
Site 12S56NVEDRSSSGSWGNGG
Site 13S58EDRSSSGSWGNGGHP
Site 14S66WGNGGHPSPSRNYGD
Site 15S68NGGHPSPSRNYGDGT
Site 16Y71HPSPSRNYGDGTPYD
Site 17T75SRNYGDGTPYDHMTS
Site 18Y77NYGDGTPYDHMTSRD
Site 19T81GTPYDHMTSRDLGSH
Site 20S87MTSRDLGSHDNLSPP
Site 21S92LGSHDNLSPPFVNSR
Site 22S98LSPPFVNSRIQSKTE
Site 23S102FVNSRIQSKTERGSY
Site 24T104NSRIQSKTERGSYSS
Site 25S108QSKTERGSYSSYGRE
Site 26Y109SKTERGSYSSYGRES
Site 27S110KTERGSYSSYGRESN
Site 28S111TERGSYSSYGRESNL
Site 29Y112ERGSYSSYGRESNLQ
Site 30S116YSSYGRESNLQGCHQ
Site 31S125LQGCHQQSLLGGDMD
Site 32T138MDMGNPGTLSPTKPG
Site 33S140MGNPGTLSPTKPGSQ
Site 34T142NPGTLSPTKPGSQYY
Site 35S146LSPTKPGSQYYQYSS
Site 36Y148PTKPGSQYYQYSSNN
Site 37Y149TKPGSQYYQYSSNNP
Site 38Y151PGSQYYQYSSNNPRR
Site 39S163PRRRPLHSSAMEVQT
Site 40S164RRRPLHSSAMEVQTK
Site 41S182KVPPGLPSSVYAPSA
Site 42Y185PGLPSSVYAPSASTA
Site 43S188PSSVYAPSASTADYN
Site 44S190SVYAPSASTADYNRD
Site 45Y194PSASTADYNRDSPGY
Site 46S198TADYNRDSPGYPSSK
Site 47Y201YNRDSPGYPSSKPAT
Site 48S203RDSPGYPSSKPATST
Site 49S204DSPGYPSSKPATSTF
Site 50T208YPSSKPATSTFPSSF
Site 51S209PSSKPATSTFPSSFF
Site 52T210SSKPATSTFPSSFFM
Site 53S213PATSTFPSSFFMQDG
Site 54S214ATSTFPSSFFMQDGH
Site 55S223FMQDGHHSSDPWSSS
Site 56S224MQDGHHSSDPWSSSS
Site 57S228HHSSDPWSSSSGMNQ
Site 58S229HSSDPWSSSSGMNQP
Site 59S230SSDPWSSSSGMNQPG
Site 60S231SDPWSSSSGMNQPGY
Site 61Y238SGMNQPGYAGMLGNS
Site 62S246AGMLGNSSHIPQSSS
Site 63S251NSSHIPQSSSYCSLH
Site 64S252SSHIPQSSSYCSLHP
Site 65S253SHIPQSSSYCSLHPH
Site 66Y254HIPQSSSYCSLHPHE
Site 67S256PQSSSYCSLHPHERL
Site 68S264LHPHERLSYPSHSSA
Site 69Y265HPHERLSYPSHSSAD
Site 70S267HERLSYPSHSSADIN
Site 71S269RLSYPSHSSADINSS
Site 72S270LSYPSHSSADINSSL
Site 73S275HSSADINSSLPPMST
Site 74S276SSADINSSLPPMSTF
Site 75S281NSSLPPMSTFHRSGT
Site 76T282SSLPPMSTFHRSGTN
Site 77T288STFHRSGTNHYSTSS
Site 78S292RSGTNHYSTSSCTPP
Site 79T293SGTNHYSTSSCTPPA
Site 80S294GTNHYSTSSCTPPAN
Site 81S295TNHYSTSSCTPPANG
Site 82T297HYSTSSCTPPANGTD
Site 83S305PPANGTDSIMANRGS
Site 84S312SIMANRGSGAAGSSQ
Site 85S317RGSGAAGSSQTGDAL
Site 86S318GSGAAGSSQTGDALG
Site 87S330ALGKALASIYSPDHT
Site 88S333KALASIYSPDHTNNS
Site 89T337SIYSPDHTNNSFSSN
Site 90S340SPDHTNNSFSSNPST
Site 91S342DHTNNSFSSNPSTPV
Site 92S343HTNNSFSSNPSTPVG
Site 93S346NSFSSNPSTPVGSPP
Site 94T347SFSSNPSTPVGSPPS
Site 95S351NPSTPVGSPPSLSAG
Site 96S363SAGTAVWSRNGGQAS
Site 97S370SRNGGQASSSPNYEG
Site 98S371RNGGQASSSPNYEGP
Site 99S372NGGQASSSPNYEGPL
Site 100Y375QASSSPNYEGPLHSL
Site 101S381NYEGPLHSLQSRIED
Site 102S408RNHAVGPSTAMPGGH
Site 103T409NHAVGPSTAMPGGHG
Site 104T439GLGSGYGTGLLSANR
Site 105S443GYGTGLLSANRHSLM
Site 106S448LLSANRHSLMVGTHR
Site 107S464DGVALRGSHSLLPNQ
Site 108S466VALRGSHSLLPNQVP
Site 109S484LPVQSATSPDLNPPQ
Site 110Y494LNPPQDPYRGMPPGL
Site 111S505PPGLQGQSVSSGSSE
Site 112S507GLQGQSVSSGSSEIK
Site 113S508LQGQSVSSGSSEIKS
Site 114S510GQSVSSGSSEIKSDD
Site 115S511QSVSSGSSEIKSDDE
Site 116S515SGSSEIKSDDEGDEN
Site 117T526GDENLQDTKSSEDKK
Site 118S528ENLQDTKSSEDKKLD
Site 119S543DDKKDIKSITSNNDD
Site 120T545KKDIKSITSNNDDED
Site 121S546KDIKSITSNNDDEDL
Site 122T554NNDDEDLTPEQKAER
Site 123S597MVQLHLKSDKPQTKL
Site 124T602LKSDKPQTKLLILHQ
Site 125S642RREEEKVSSEPPPLS
Site 126S643REEEKVSSEPPPLSL
Site 127S649SSEPPPLSLAGPHPG
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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