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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SIAT1 (Glycosyltransferase)
Full Name:
Beta-galactoside alpha-2,6-sialyltransferase 1
Alias:
B-cell antigen CD75; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2;6-sialyltransferase 1; EC 2.4.99.1; ST6Gal I; ST6GAL1
Type:
Enzyme, CMP-sialic acid transferase
Mass (Da):
46605
Number AA:
406
UniProt ID:
P15907
International Prot ID:
IPI00013887
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
GO:0030173
Uniprot
OncoNet
Molecular Function:
GO:0003835
PhosphoSite+
KinaseNET
Biological Process:
GO:0006959
GO:0006486
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S33
W
K
E
K
K
K
G
S
Y
Y
D
S
F
K
L
Site 2
Y35
E
K
K
K
G
S
Y
Y
D
S
F
K
L
Q
T
Site 3
S37
K
K
G
S
Y
Y
D
S
F
K
L
Q
T
K
E
Site 4
S58
L
G
K
L
A
M
G
S
D
S
Q
S
V
S
S
Site 5
S60
K
L
A
M
G
S
D
S
Q
S
V
S
S
S
S
Site 6
S62
A
M
G
S
D
S
Q
S
V
S
S
S
S
T
Q
Site 7
S64
G
S
D
S
Q
S
V
S
S
S
S
T
Q
D
P
Site 8
S65
S
D
S
Q
S
V
S
S
S
S
T
Q
D
P
H
Site 9
S66
D
S
Q
S
V
S
S
S
S
T
Q
D
P
H
R
Site 10
S67
S
Q
S
V
S
S
S
S
T
Q
D
P
H
R
G
Site 11
T68
Q
S
V
S
S
S
S
T
Q
D
P
H
R
G
R
Site 12
T77
D
P
H
R
G
R
Q
T
L
G
S
L
R
G
L
Site 13
S80
R
G
R
Q
T
L
G
S
L
R
G
L
A
K
A
Site 14
S92
A
K
A
K
P
E
A
S
F
Q
V
W
N
K
D
Site 15
S100
F
Q
V
W
N
K
D
S
S
S
K
N
L
I
P
Site 16
S101
Q
V
W
N
K
D
S
S
S
K
N
L
I
P
R
Site 17
S102
V
W
N
K
D
S
S
S
K
N
L
I
P
R
L
Site 18
Y116
L
Q
K
I
W
K
N
Y
L
S
M
N
K
Y
K
Site 19
Y122
N
Y
L
S
M
N
K
Y
K
V
S
Y
K
G
P
Site 20
S125
S
M
N
K
Y
K
V
S
Y
K
G
P
G
P
G
Site 21
Y126
M
N
K
Y
K
V
S
Y
K
G
P
G
P
G
I
Site 22
S136
P
G
P
G
I
K
F
S
A
E
A
L
R
C
H
Site 23
T156
N
V
S
M
V
E
V
T
D
F
P
F
N
T
S
Site 24
Y168
N
T
S
E
W
E
G
Y
L
P
K
E
S
I
R
Site 25
S173
E
G
Y
L
P
K
E
S
I
R
T
K
A
G
P
Site 26
T176
L
P
K
E
S
I
R
T
K
A
G
P
W
G
R
Site 27
S195
S
S
A
G
S
L
K
S
S
Q
L
G
R
E
I
Site 28
S196
S
A
G
S
L
K
S
S
Q
L
G
R
E
I
D
Site 29
T227
Q
Q
D
V
G
T
K
T
T
I
R
L
M
N
S
Site 30
S234
T
T
I
R
L
M
N
S
Q
L
V
T
T
E
K
Site 31
T238
L
M
N
S
Q
L
V
T
T
E
K
R
F
L
K
Site 32
S247
E
K
R
F
L
K
D
S
L
Y
N
E
G
I
L
Site 33
Y262
I
V
W
D
P
S
V
Y
H
S
D
I
P
K
W
Site 34
Y294
L
H
P
N
Q
P
F
Y
I
L
K
P
Q
M
P
Site 35
S312
W
D
I
L
Q
E
I
S
P
E
E
I
Q
P
N
Site 36
S322
E
I
Q
P
N
P
P
S
S
G
M
L
G
I
I
Site 37
Y341
L
C
D
Q
V
D
I
Y
E
F
L
P
S
K
R
Site 38
S346
D
I
Y
E
F
L
P
S
K
R
K
T
D
V
C
Site 39
T350
F
L
P
S
K
R
K
T
D
V
C
Y
Y
Y
Q
Site 40
Y354
K
R
K
T
D
V
C
Y
Y
Y
Q
K
F
F
D
Site 41
Y355
R
K
T
D
V
C
Y
Y
Y
Q
K
F
F
D
S
Site 42
Y356
K
T
D
V
C
Y
Y
Y
Q
K
F
F
D
S
A
Site 43
Y369
S
A
C
T
M
G
A
Y
H
P
L
L
Y
E
K
Site 44
Y374
G
A
Y
H
P
L
L
Y
E
K
N
L
V
K
H
Site 45
Y391
Q
G
T
D
E
D
I
Y
L
L
G
K
A
T
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation