PhosphoNET

           
Protein Info 
   
Short Name:  Kv1.2
Full Name:  Potassium voltage-gated channel subfamily A member 2
Alias:  CIK2; HBK5; HK4; HUKIV; HuKIV; KCNA2; MK2; NGK1; Potassium voltage-gated channel, shaker-related subfamily, member 2; RBK2; Voltage-gated potassium channel Kv1.2; Voltage-gated potassium channel Kv12; Voltage-gated potassium channel subunit Kv1.2
Type:  Channel protein, potassium
Mass (Da):  56717
Number AA:  499
UniProt ID:  P16389
International Prot ID:  IPI00028134
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0008076     Uniprot OncoNet
Molecular Function:  GO:0005251  GO:0030955   PhosphoSite+ KinaseNET
Biological Process:  GO:0006813  GO:0055085   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T22LPGHPQDTYDPEADH
Site 2Y23PGHPQDTYDPEADHE
Site 3S40ERVVINISGLRFETQ
Site 4T46ISGLRFETQLKTLAQ
Site 5T50RFETQLKTLAQFPET
Site 6T57TLAQFPETLLGDPKK
Site 7Y68DPKKRMRYFDPLRNE
Site 8Y76FDPLRNEYFFDRNRP
Site 9S84FFDRNRPSFDAILYY
Site 10Y90PSFDAILYYYQSGGR
Site 11Y91SFDAILYYYQSGGRL
Site 12Y92FDAILYYYQSGGRLR
Site 13S94AILYYYQSGGRLRRP
Site 14S110NVPLDIFSEEIRFYE
Site 15Y116FSEEIRFYELGEEAM
Site 16Y132MFREDEGYIKEEERP
Site 17Y155QVWLLFEYPESSGPA
Site 18T201DMHGSGVTFHTYSNS
Site 19T204GSGVTFHTYSNSTIG
Site 20Y205SGVTFHTYSNSTIGY
Site 21S208TFHTYSNSTIGYQQS
Site 22Y212YSNSTIGYQQSTSFT
Site 23S215STIGYQQSTSFTDPF
Site 24S217IGYQQSTSFTDPFFI
Site 25T219YQQSTSFTDPFFIVE
Site 26S308VFRIFKLSRHSKGLQ
Site 27S311IFKLSRHSKGLQILG
Site 28S356AEADERESQFPSIPD
Site 29Y415VIVSNFNYFYHRETE
Site 30Y417VSNFNYFYHRETEGE
Site 31T421NYFYHRETEGEEQAQ
Site 32Y429EGEEQAQYLQVTSCP
Site 33T433QAQYLQVTSCPKIPS
Site 34S434AQYLQVTSCPKIPSS
Site 35S440TSCPKIPSSPDLKKS
Site 36S441SCPKIPSSPDLKKSR
Site 37S447SSPDLKKSRSASTIS
Site 38S449PDLKKSRSASTISKS
Site 39S451LKKSRSASTISKSDY
Site 40T452KKSRSASTISKSDYM
Site 41S454SRSASTISKSDYMEI
Site 42S456SASTISKSDYMEIQE
Site 43Y458STISKSDYMEIQEGV
Site 44T479FREENLKTANCTLAN
Site 45Y489CTLANTNYVNITKML
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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