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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EPB42
Full Name:
Erythrocyte membrane protein band 4.2
Alias:
Type:
Mass (Da):
77009
Number AA:
691
UniProt ID:
P16452
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
G
Q
A
L
G
I
K
S
C
D
F
Q
A
A
R
Site 2
T23
R
N
N
E
E
H
H
T
K
A
L
S
S
R
R
Site 3
S27
E
H
H
T
K
A
L
S
S
R
R
L
F
V
R
Site 4
S28
H
H
T
K
A
L
S
S
R
R
L
F
V
R
R
Site 5
T75
Q
P
S
K
I
N
R
T
Q
A
T
F
P
I
S
Site 6
T78
K
I
N
R
T
Q
A
T
F
P
I
S
S
L
G
Site 7
S91
L
G
D
R
K
W
W
S
A
V
V
E
E
R
D
Site 8
S101
V
E
E
R
D
A
Q
S
W
T
I
S
V
T
T
Site 9
S105
D
A
Q
S
W
T
I
S
V
T
T
P
A
D
A
Site 10
Y158
N
E
A
Q
R
M
E
Y
L
L
N
Q
N
G
L
Site 11
S192
E
G
D
V
I
D
L
S
L
R
L
L
S
K
D
Site 12
S197
D
L
S
L
R
L
L
S
K
D
K
Q
V
E
K
Site 13
S206
D
K
Q
V
E
K
W
S
Q
P
V
H
V
A
R
Site 14
T230
K
E
Q
R
V
L
P
T
P
Q
T
Q
A
T
Q
Site 15
T233
R
V
L
P
T
P
Q
T
Q
A
T
Q
E
G
A
Site 16
S248
L
L
N
K
R
R
G
S
V
P
I
L
R
Q
W
Site 17
T257
P
I
L
R
Q
W
L
T
G
R
G
R
P
V
Y
Site 18
Y264
T
G
R
G
R
P
V
Y
D
G
Q
A
W
V
L
Site 19
T291
I
P
A
R
V
V
T
T
F
A
S
A
Q
G
T
Site 20
S294
R
V
V
T
T
F
A
S
A
Q
G
T
G
G
R
Site 21
Y307
G
R
L
L
I
D
E
Y
Y
N
E
E
G
L
Q
Site 22
Y308
R
L
L
I
D
E
Y
Y
N
E
E
G
L
Q
N
Site 23
T335
T
S
T
E
C
W
M
T
R
P
A
L
P
Q
G
Site 24
S352
G
W
Q
I
L
H
P
S
A
P
N
G
G
G
V
Site 25
T375
V
R
A
V
K
E
G
T
L
G
L
T
P
A
V
Site 26
T403
W
K
C
C
E
D
G
T
L
E
L
T
D
S
N
Site 27
T407
E
D
G
T
L
E
L
T
D
S
N
T
K
Y
V
Site 28
S409
G
T
L
E
L
T
D
S
N
T
K
Y
V
G
N
Site 29
T411
L
E
L
T
D
S
N
T
K
Y
V
G
N
N
I
Site 30
Y413
L
T
D
S
N
T
K
Y
V
G
N
N
I
S
T
Site 31
S419
K
Y
V
G
N
N
I
S
T
K
G
V
G
S
D
Site 32
S425
I
S
T
K
G
V
G
S
D
R
C
E
D
I
T
Site 33
T432
S
D
R
C
E
D
I
T
Q
N
Y
K
Y
P
E
Site 34
Y435
C
E
D
I
T
Q
N
Y
K
Y
P
E
G
S
L
Site 35
Y437
D
I
T
Q
N
Y
K
Y
P
E
G
S
L
Q
E
Site 36
S441
N
Y
K
Y
P
E
G
S
L
Q
E
K
E
V
L
Site 37
S468
D
N
G
I
R
P
P
S
L
E
T
A
S
P
L
Site 38
S494
L
R
G
D
A
Q
I
S
V
T
L
V
N
H
S
Site 39
T534
W
R
K
K
L
H
L
T
L
S
A
N
L
E
K
Site 40
S550
I
T
I
G
L
F
F
S
N
F
E
R
N
P
P
Site 41
T560
E
R
N
P
P
E
N
T
F
L
R
L
T
A
M
Site 42
T565
E
N
T
F
L
R
L
T
A
M
A
T
H
S
E
Site 43
T569
L
R
L
T
A
M
A
T
H
S
E
S
N
L
S
Site 44
S576
T
H
S
E
S
N
L
S
C
F
A
Q
E
D
I
Site 45
T605
A
E
Q
Y
Q
P
L
T
A
S
V
S
L
Q
N
Site 46
S607
Q
Y
Q
P
L
T
A
S
V
S
L
Q
N
S
L
Site 47
S609
Q
P
L
T
A
S
V
S
L
Q
N
S
L
D
A
Site 48
S613
A
S
V
S
L
Q
N
S
L
D
A
P
M
E
D
Site 49
S636
G
L
I
H
R
E
R
S
Y
R
F
R
S
V
W
Site 50
Y637
L
I
H
R
E
R
S
Y
R
F
R
S
V
W
P
Site 51
S641
E
R
S
Y
R
F
R
S
V
W
P
E
N
T
M
Site 52
S681
Q
N
L
T
N
Y
K
S
V
T
V
V
A
P
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation