PhosphoNET

           
Protein Info 
   
Short Name:  FAH
Full Name:  Fumarylacetoacetase
Alias:  Beta-diketonase; EC 3.7.1.2; FAAA; Fumarylacetoacetate hydrolase
Type:  Enzyme - Hydrolase
Mass (Da):  46374
Number AA:  419
UniProt ID:  P16930
International Prot ID:  IPI00031708
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005829     Uniprot OncoNet
Molecular Function:  GO:0005509  GO:0004334  GO:0000287 PhosphoSite+ KinaseNET
Biological Process:  GO:0006559  GO:0006572   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y19FPIHNLPYGVFSTRG
Site 2S23NLPYGVFSTRGDPRP
Site 3T51SIIKHLFTGPVLSKH
Site 4S56LFTGPVLSKHQDVFN
Site 5S69FNQPTLNSFMGLGQA
Site 6S92LQNLLSVSQARLRDD
Site 7T100QARLRDDTELRKCAF
Site 8Y124LPATIGDYTDFYSSR
Site 9T125PATIGDYTDFYSSRQ
Site 10Y128IGDYTDFYSSRQHAT
Site 11S165GYHGRASSVVVSGTP
Site 12S169RASSVVVSGTPIRRP
Site 13T171SSVVVSGTPIRRPMG
Site 14S185GQMKPDDSKPPVYGA
Site 15Y190DDSKPPVYGACKLLD
Site 16S219LGEPIPISKAHEHIF
Site 17Y244RDIQKWEYVPLGPFL
Site 18Y286QDPRPLPYLCHDEPY
Site 19Y293YLCHDEPYTFDINLS
Site 20T294LCHDEPYTFDINLSV
Site 21S300YTFDINLSVNLKGEG
Site 22T313EGMSQAATICKSNFK
Site 23Y323KSNFKYMYWTMLQQL
Site 24S348RPGDLLASGTISGPE
Site 25S352LLASGTISGPEPENF
Site 26S361PEPENFGSMLELSWK
Site 27S366FGSMLELSWKGTKPI
Site 28T370LELSWKGTKPIDLGN
Site 29T393DGDEVIITGYCQGDG
Site 30Y395DEVIITGYCQGDGYR
Site 31Y401GYCQGDGYRIGFGQC
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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