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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF12
Full Name:
Zinc finger protein 12
Alias:
GIOT3; GIOT-3; Gonadotropin-inducible transcription repressor 3; KOX3; Zinc finger protein 325; ZNF325
Type:
Unknown function
Mass (Da):
58223
Number AA:
501
UniProt ID:
P17014
International Prot ID:
IPI00645116
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
N
K
S
L
G
P
V
S
F
K
D
V
A
V
D
Site 2
T18
K
D
V
A
V
D
F
T
Q
E
E
W
Q
Q
L
Site 3
T32
L
D
P
E
Q
K
I
T
Y
R
D
V
M
L
E
Site 4
Y41
R
D
V
M
L
E
N
Y
S
N
L
V
S
V
G
Site 5
S77
E
G
E
F
L
L
Q
S
Y
P
D
E
V
W
Q
Site 6
Y78
G
E
F
L
L
Q
S
Y
P
D
E
V
W
Q
T
Site 7
T103
E
N
K
P
S
R
Q
T
V
F
I
E
T
L
I
Site 8
T120
R
G
N
V
P
G
K
T
F
D
V
E
T
N
P
Site 9
T125
G
K
T
F
D
V
E
T
N
P
V
P
S
R
K
Site 10
S138
R
K
I
A
Y
K
N
S
L
C
D
S
C
E
K
Site 11
S142
Y
K
N
S
L
C
D
S
C
E
K
C
L
T
S
Site 12
T148
D
S
C
E
K
C
L
T
S
V
S
E
Y
I
S
Site 13
S149
S
C
E
K
C
L
T
S
V
S
E
Y
I
S
S
Site 14
S151
E
K
C
L
T
S
V
S
E
Y
I
S
S
D
G
Site 15
Y153
C
L
T
S
V
S
E
Y
I
S
S
D
G
S
Y
Site 16
S155
T
S
V
S
E
Y
I
S
S
D
G
S
Y
A
R
Site 17
S156
S
V
S
E
Y
I
S
S
D
G
S
Y
A
R
M
Site 18
S159
E
Y
I
S
S
D
G
S
Y
A
R
M
K
A
D
Site 19
Y160
Y
I
S
S
D
G
S
Y
A
R
M
K
A
D
E
Site 20
S169
R
M
K
A
D
E
C
S
G
C
G
K
S
L
L
Site 21
S174
E
C
S
G
C
G
K
S
L
L
H
I
K
L
E
Site 22
T183
L
H
I
K
L
E
K
T
H
P
G
D
Q
A
Y
Site 23
Y190
T
H
P
G
D
Q
A
Y
E
F
N
Q
N
G
E
Site 24
T200
N
Q
N
G
E
P
Y
T
L
N
E
E
S
L
Y
Site 25
Y207
T
L
N
E
E
S
L
Y
Q
K
I
R
I
L
E
Site 26
Y241
N
H
M
E
E
K
P
Y
K
W
N
G
S
E
I
Site 27
Y269
S
H
M
E
M
K
P
Y
E
C
S
E
C
G
K
Site 28
T290
K
F
I
I
H
Q
R
T
H
T
G
E
K
P
Y
Site 29
T292
I
I
H
Q
R
T
H
T
G
E
K
P
Y
E
C
Site 30
Y297
T
H
T
G
E
K
P
Y
E
C
N
Q
C
G
K
Site 31
T313
F
C
Q
K
G
T
L
T
V
H
Q
R
T
H
T
Site 32
T318
T
L
T
V
H
Q
R
T
H
T
G
E
K
P
Y
Site 33
T320
T
V
H
Q
R
T
H
T
G
E
K
P
Y
E
C
Site 34
Y325
T
H
T
G
E
K
P
Y
E
C
N
E
C
G
K
Site 35
T346
H
L
I
Q
H
Q
R
T
H
S
G
E
K
P
Y
Site 36
S348
I
Q
H
Q
R
T
H
S
G
E
K
P
Y
E
C
Site 37
Y353
T
H
S
G
E
K
P
Y
E
C
S
Y
C
G
K
Site 38
S356
G
E
K
P
Y
E
C
S
Y
C
G
K
S
F
C
Site 39
Y357
E
K
P
Y
E
C
S
Y
C
G
K
S
F
C
Q
Site 40
T366
G
K
S
F
C
Q
K
T
H
L
T
Q
H
Q
R
Site 41
S376
T
Q
H
Q
R
T
H
S
G
E
R
P
Y
V
C
Site 42
Y381
T
H
S
G
E
R
P
Y
V
C
H
D
C
G
K
Site 43
T389
V
C
H
D
C
G
K
T
F
S
Q
K
S
A
L
Site 44
S391
H
D
C
G
K
T
F
S
Q
K
S
A
L
N
D
Site 45
S394
G
K
T
F
S
Q
K
S
A
L
N
D
H
Q
K
Site 46
Y409
I
H
T
G
V
K
L
Y
K
C
S
E
C
G
K
Site 47
S422
G
K
C
F
C
R
K
S
T
L
T
T
H
L
R
Site 48
T423
K
C
F
C
R
K
S
T
L
T
T
H
L
R
T
Site 49
T425
F
C
R
K
S
T
L
T
T
H
L
R
T
H
T
Site 50
T426
C
R
K
S
T
L
T
T
H
L
R
T
H
T
G
Site 51
T430
T
L
T
T
H
L
R
T
H
T
G
E
K
P
Y
Site 52
T432
T
T
H
L
R
T
H
T
G
E
K
P
Y
E
C
Site 53
S447
N
E
C
G
K
F
F
S
R
L
S
Y
L
T
V
Site 54
S450
G
K
F
F
S
R
L
S
Y
L
T
V
H
Y
R
Site 55
Y451
K
F
F
S
R
L
S
Y
L
T
V
H
Y
R
T
Site 56
T453
F
S
R
L
S
Y
L
T
V
H
Y
R
T
H
S
Site 57
Y456
L
S
Y
L
T
V
H
Y
R
T
H
S
G
E
K
Site 58
S460
T
V
H
Y
R
T
H
S
G
E
K
P
Y
E
C
Site 59
Y465
T
H
S
G
E
K
P
Y
E
C
T
E
C
G
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation