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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF16
Full Name:
Zinc finger protein 16
Alias:
KOX9
Type:
Nucleus protein
Mass (Da):
76472
Number AA:
682
UniProt ID:
P17020
International Prot ID:
IPI00299749
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
E
E
A
E
M
E
L
S
V
P
G
P
S
P
W
Site 2
S21
E
L
S
V
P
G
P
S
P
W
T
P
A
A
Q
Site 3
T24
V
P
G
P
S
P
W
T
P
A
A
Q
A
R
V
Site 4
T47
P
G
S
A
A
C
G
T
P
C
C
S
D
T
E
Site 5
T53
G
T
P
C
C
S
D
T
E
L
E
A
I
C
P
Site 6
Y62
L
E
A
I
C
P
H
Y
Q
Q
P
D
C
D
T
Site 7
T69
Y
Q
Q
P
D
C
D
T
R
T
E
D
K
E
F
Site 8
T71
Q
P
D
C
D
T
R
T
E
D
K
E
F
L
H
Site 9
S88
D
I
H
E
D
L
E
S
Q
A
E
I
S
E
N
Site 10
S101
E
N
Y
A
G
D
V
S
Q
V
P
E
L
G
D
Site 11
S114
G
D
L
C
D
D
V
S
E
R
D
W
G
V
P
Site 12
S129
E
G
R
R
L
P
Q
S
L
S
Q
E
G
D
F
Site 13
S131
R
R
L
P
Q
S
L
S
Q
E
G
D
F
T
P
Site 14
S160
L
D
C
N
G
F
D
S
R
F
S
L
S
P
N
Site 15
S163
N
G
F
D
S
R
F
S
L
S
P
N
L
M
A
Site 16
S165
F
D
S
R
F
S
L
S
P
N
L
M
A
C
Q
Site 17
Y183
T
E
E
R
P
H
P
Y
D
M
G
G
Q
S
F
Site 18
S189
P
Y
D
M
G
G
Q
S
F
Q
H
S
V
D
L
Site 19
S193
G
G
Q
S
F
Q
H
S
V
D
L
T
G
H
E
Site 20
T197
F
Q
H
S
V
D
L
T
G
H
E
G
V
P
T
Site 21
T204
T
G
H
E
G
V
P
T
A
E
S
P
L
I
C
Site 22
S207
E
G
V
P
T
A
E
S
P
L
I
C
N
E
C
Site 23
S247
D
D
C
G
K
T
F
S
Q
N
S
V
L
K
N
Site 24
S250
G
K
T
F
S
Q
N
S
V
L
K
N
R
H
R
Site 25
S258
V
L
K
N
R
H
R
S
H
M
S
E
K
A
Y
Site 26
Y265
S
H
M
S
E
K
A
Y
Q
C
S
E
C
G
K
Site 27
S268
S
E
K
A
Y
Q
C
S
E
C
G
K
A
F
R
Site 28
S278
G
K
A
F
R
G
H
S
D
F
S
R
H
Q
S
Site 29
S281
F
R
G
H
S
D
F
S
R
H
Q
S
H
H
S
Site 30
S285
S
D
F
S
R
H
Q
S
H
H
S
S
E
R
P
Site 31
S288
S
R
H
Q
S
H
H
S
S
E
R
P
Y
M
C
Site 32
Y293
H
H
S
S
E
R
P
Y
M
C
N
E
C
G
K
Site 33
S303
N
E
C
G
K
A
F
S
Q
N
S
S
L
K
K
Site 34
S306
G
K
A
F
S
Q
N
S
S
L
K
K
H
Q
K
Site 35
S307
K
A
F
S
Q
N
S
S
L
K
K
H
Q
K
S
Site 36
S314
S
L
K
K
H
Q
K
S
H
M
S
E
K
P
Y
Site 37
Y321
S
H
M
S
E
K
P
Y
E
C
N
E
C
G
K
Site 38
S333
C
G
K
A
F
R
R
S
S
N
L
I
Q
H
Q
Site 39
S334
G
K
A
F
R
R
S
S
N
L
I
Q
H
Q
R
Site 40
Y349
I
H
S
G
E
K
P
Y
V
C
S
E
C
G
K
Site 41
S352
G
E
K
P
Y
V
C
S
E
C
G
K
A
F
R
Site 42
S361
C
G
K
A
F
R
R
S
S
N
L
I
K
H
H
Site 43
S362
G
K
A
F
R
R
S
S
N
L
I
K
H
H
R
Site 44
T370
N
L
I
K
H
H
R
T
H
T
G
E
K
P
F
Site 45
T372
I
K
H
H
R
T
H
T
G
E
K
P
F
E
C
Site 46
S387
G
E
C
G
K
A
F
S
Q
S
A
H
L
R
K
Site 47
S389
C
G
K
A
F
S
Q
S
A
H
L
R
K
H
Q
Site 48
T400
R
K
H
Q
R
V
H
T
G
E
K
P
Y
E
C
Site 49
Y405
V
H
T
G
E
K
P
Y
E
C
N
D
C
G
K
Site 50
S415
N
D
C
G
K
P
F
S
R
V
S
N
L
I
K
Site 51
S418
G
K
P
F
S
R
V
S
N
L
I
K
H
H
R
Site 52
T428
I
K
H
H
R
V
H
T
G
E
K
P
Y
K
C
Site 53
S436
G
E
K
P
Y
K
C
S
D
C
G
K
A
F
S
Site 54
S443
S
D
C
G
K
A
F
S
Q
S
S
S
L
I
Q
Site 55
S445
C
G
K
A
F
S
Q
S
S
S
L
I
Q
H
R
Site 56
S446
G
K
A
F
S
Q
S
S
S
L
I
Q
H
R
R
Site 57
S447
K
A
F
S
Q
S
S
S
L
I
Q
H
R
R
I
Site 58
T456
I
Q
H
R
R
I
H
T
G
E
K
P
H
V
C
Site 59
S471
N
V
C
G
K
A
F
S
Y
S
S
V
L
R
K
Site 60
Y472
V
C
G
K
A
F
S
Y
S
S
V
L
R
K
H
Site 61
S473
C
G
K
A
F
S
Y
S
S
V
L
R
K
H
Q
Site 62
S474
G
K
A
F
S
Y
S
S
V
L
R
K
H
Q
I
Site 63
T484
R
K
H
Q
I
I
H
T
G
E
K
P
Y
R
C
Site 64
S492
G
E
K
P
Y
R
C
S
V
C
G
K
A
F
S
Site 65
S501
C
G
K
A
F
S
H
S
S
A
L
I
Q
H
Q
Site 66
S502
G
K
A
F
S
H
S
S
A
L
I
Q
H
Q
G
Site 67
Y517
V
H
T
G
D
K
P
Y
A
C
H
E
C
G
K
Site 68
T525
A
C
H
E
C
G
K
T
F
G
R
S
S
N
L
Site 69
S529
C
G
K
T
F
G
R
S
S
N
L
I
L
H
Q
Site 70
S530
G
K
T
F
G
R
S
S
N
L
I
L
H
Q
R
Site 71
T540
I
L
H
Q
R
V
H
T
G
E
K
P
Y
E
C
Site 72
Y545
V
H
T
G
E
K
P
Y
E
C
T
E
C
G
K
Site 73
T553
E
C
T
E
C
G
K
T
F
S
Q
S
S
T
L
Site 74
S555
T
E
C
G
K
T
F
S
Q
S
S
T
L
I
Q
Site 75
S557
C
G
K
T
F
S
Q
S
S
T
L
I
Q
H
Q
Site 76
T559
K
T
F
S
Q
S
S
T
L
I
Q
H
Q
R
I
Site 77
S586
G
K
A
F
N
R
S
S
N
L
I
H
H
Q
K
Site 78
T596
I
H
H
Q
K
V
H
T
G
E
K
P
Y
T
C
Site 79
Y601
V
H
T
G
E
K
P
Y
T
C
V
E
C
G
K
Site 80
T602
H
T
G
E
K
P
Y
T
C
V
E
C
G
K
G
Site 81
S611
V
E
C
G
K
G
F
S
Q
S
S
H
L
I
Q
Site 82
S613
C
G
K
G
F
S
Q
S
S
H
L
I
Q
H
Q
Site 83
S614
G
K
G
F
S
Q
S
S
H
L
I
Q
H
Q
I
Site 84
Y629
I
H
T
G
E
R
P
Y
K
C
S
E
C
G
K
Site 85
S632
G
E
R
P
Y
K
C
S
E
C
G
K
A
F
S
Site 86
S639
S
E
C
G
K
A
F
S
Q
R
S
V
L
I
Q
Site 87
S642
G
K
A
F
S
Q
R
S
V
L
I
Q
H
Q
R
Site 88
T652
I
Q
H
Q
R
I
H
T
G
V
K
P
Y
D
C
Site 89
S667
A
A
C
G
K
A
F
S
Q
R
S
K
L
I
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation