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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF18
Full Name:
Zinc finger protein 18
Alias:
Heart development-specific gene 1 protein;Zinc finger protein 535;Zinc finger protein KOX11;Zinc finger protein with KRAB and SCAN domains 6
Type:
Mass (Da):
62288
Number AA:
549
UniProt ID:
P17022
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S21
S
L
A
K
A
E
D
S
Q
F
S
E
S
D
A
Site 2
S26
E
D
S
Q
F
S
E
S
D
A
A
L
Q
E
E
Site 3
S35
A
A
L
Q
E
E
L
S
S
P
E
T
A
R
Q
Site 4
S36
A
L
Q
E
E
L
S
S
P
E
T
A
R
Q
L
Site 5
T39
E
E
L
S
S
P
E
T
A
R
Q
L
F
R
Q
Site 6
Y49
Q
L
F
R
Q
F
R
Y
Q
V
M
S
G
P
H
Site 7
S53
Q
F
R
Y
Q
V
M
S
G
P
H
E
T
L
K
Site 8
S108
V
R
K
Q
C
P
G
S
G
E
E
A
V
T
L
Site 9
T114
G
S
G
E
E
A
V
T
L
V
E
S
L
K
G
Site 10
S118
E
A
V
T
L
V
E
S
L
K
G
D
P
Q
R
Site 11
S141
V
L
G
Q
D
I
L
S
E
K
M
E
S
P
S
Site 12
S146
I
L
S
E
K
M
E
S
P
S
C
Q
V
G
E
Site 13
S148
S
E
K
M
E
S
P
S
C
Q
V
G
E
V
E
Site 14
S170
Q
E
L
G
L
E
N
S
S
S
G
P
G
E
L
Site 15
S171
E
L
G
L
E
N
S
S
S
G
P
G
E
L
L
Site 16
S172
L
G
L
E
N
S
S
S
G
P
G
E
L
L
S
Site 17
S179
S
G
P
G
E
L
L
S
H
I
V
K
E
E
S
Site 18
S186
S
H
I
V
K
E
E
S
D
T
E
A
E
L
A
Site 19
T188
I
V
K
E
E
S
D
T
E
A
E
L
A
L
A
Site 20
S197
A
E
L
A
L
A
A
S
Q
P
A
R
L
E
E
Site 21
S215
R
D
Q
D
L
G
A
S
L
L
P
A
A
P
Q
Site 22
S249
E
T
Y
G
K
M
V
S
G
A
G
I
S
H
P
Site 23
S254
M
V
S
G
A
G
I
S
H
P
K
S
D
L
T
Site 24
S258
A
G
I
S
H
P
K
S
D
L
T
N
S
I
E
Site 25
T261
S
H
P
K
S
D
L
T
N
S
I
E
F
G
E
Site 26
S263
P
K
S
D
L
T
N
S
I
E
F
G
E
E
L
Site 27
Y274
G
E
E
L
A
G
I
Y
L
H
V
N
E
K
I
Site 28
T285
N
E
K
I
P
R
P
T
C
I
G
D
R
Q
E
Site 29
S312
D
Q
E
L
L
H
A
S
C
Q
A
S
G
E
V
Site 30
S316
L
H
A
S
C
Q
A
S
G
E
V
P
S
Q
A
Site 31
S321
Q
A
S
G
E
V
P
S
Q
A
S
L
R
G
F
Site 32
S324
G
E
V
P
S
Q
A
S
L
R
G
F
F
T
E
Site 33
T330
A
S
L
R
G
F
F
T
E
D
E
P
G
C
F
Site 34
S360
E
G
T
G
E
Q
L
S
P
Q
E
R
I
S
E
Site 35
S366
L
S
P
Q
E
R
I
S
E
K
Q
L
G
Q
H
Site 36
S383
N
P
H
S
G
E
M
S
T
M
W
L
E
E
K
Site 37
T393
W
L
E
E
K
R
E
T
S
Q
K
G
Q
P
R
Site 38
S394
L
E
E
K
R
E
T
S
Q
K
G
Q
P
R
A
Site 39
T409
P
M
A
Q
K
L
P
T
C
R
E
C
G
K
T
Site 40
Y418
R
E
C
G
K
T
F
Y
R
N
S
Q
L
I
F
Site 41
S421
G
K
T
F
Y
R
N
S
Q
L
I
F
H
Q
R
Site 42
T431
I
F
H
Q
R
T
H
T
G
E
T
Y
F
Q
C
Site 43
Y435
R
T
H
T
G
E
T
Y
F
Q
C
T
I
C
K
Site 44
S448
C
K
K
A
F
L
R
S
S
D
F
V
K
H
Q
Site 45
S449
K
K
A
F
L
R
S
S
D
F
V
K
H
Q
R
Site 46
T457
D
F
V
K
H
Q
R
T
H
T
G
E
K
P
C
Site 47
T459
V
K
H
Q
R
T
H
T
G
E
K
P
C
K
C
Site 48
Y468
E
K
P
C
K
C
D
Y
C
G
K
G
F
S
D
Site 49
S474
D
Y
C
G
K
G
F
S
D
F
S
G
L
R
H
Site 50
S477
G
K
G
F
S
D
F
S
G
L
R
H
H
E
K
Site 51
T487
R
H
H
E
K
I
H
T
G
E
K
P
Y
K
C
Site 52
Y492
I
H
T
G
E
K
P
Y
K
C
P
I
C
E
K
Site 53
S505
E
K
S
F
I
Q
R
S
N
F
N
R
H
Q
R
Site 54
T515
N
R
H
Q
R
V
H
T
G
E
K
P
Y
K
C
Site 55
Y520
V
H
T
G
E
K
P
Y
K
C
S
H
C
G
K
Site 56
S523
G
E
K
P
Y
K
C
S
H
C
G
K
S
F
S
Site 57
S528
K
C
S
H
C
G
K
S
F
S
W
S
S
S
L
Site 58
S530
S
H
C
G
K
S
F
S
W
S
S
S
L
D
K
Site 59
S532
C
G
K
S
F
S
W
S
S
S
L
D
K
H
Q
Site 60
S534
K
S
F
S
W
S
S
S
L
D
K
H
Q
R
S
Site 61
S541
S
L
D
K
H
Q
R
S
H
L
G
K
K
P
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation