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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF22
Full Name:
Zinc finger protein 22
Alias:
HKR-T1; KOX 15; KOX15; KROX26; Krox-26 protein; Zfp422; Zinc finger protein KOX15; ZNF422
Type:
DNA binding protein
Mass (Da):
25897
Number AA:
224
UniProt ID:
P17026
International Prot ID:
IPI00215890
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005730
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0042476
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
A
K
P
K
A
G
I
S
R
S
S
S
Q
G
K
Site 2
S13
P
K
A
G
I
S
R
S
S
S
Q
G
K
A
Y
Site 3
S14
K
A
G
I
S
R
S
S
S
Q
G
K
A
Y
E
Site 4
S15
A
G
I
S
R
S
S
S
Q
G
K
A
Y
E
N
Site 5
Y20
S
S
S
Q
G
K
A
Y
E
N
K
R
K
T
G
Site 6
T26
A
Y
E
N
K
R
K
T
G
R
Q
R
Q
K
W
Site 7
S41
G
M
T
I
R
F
D
S
S
F
S
R
L
R
R
Site 8
S42
M
T
I
R
F
D
S
S
F
S
R
L
R
R
S
Site 9
S44
I
R
F
D
S
S
F
S
R
L
R
R
S
L
D
Site 10
S49
S
F
S
R
L
R
R
S
L
D
D
K
P
Y
K
Site 11
Y55
R
S
L
D
D
K
P
Y
K
C
T
E
C
E
K
Site 12
T58
D
D
K
P
Y
K
C
T
E
C
E
K
S
F
S
Site 13
S63
K
C
T
E
C
E
K
S
F
S
Q
S
S
T
L
Site 14
S65
T
E
C
E
K
S
F
S
Q
S
S
T
L
F
Q
Site 15
S67
C
E
K
S
F
S
Q
S
S
T
L
F
Q
H
Q
Site 16
T69
K
S
F
S
Q
S
S
T
L
F
Q
H
Q
K
I
Site 17
S91
K
C
A
D
C
G
K
S
F
F
Q
S
S
N
L
Site 18
S95
C
G
K
S
F
F
Q
S
S
N
L
I
Q
H
R
Site 19
S96
G
K
S
F
F
Q
S
S
N
L
I
Q
H
R
R
Site 20
T106
I
Q
H
R
R
I
H
T
G
E
K
P
Y
K
C
Site 21
S119
K
C
D
E
C
G
E
S
F
K
Q
S
S
N
L
Site 22
S123
C
G
E
S
F
K
Q
S
S
N
L
I
Q
H
Q
Site 23
T134
I
Q
H
Q
R
I
H
T
G
E
K
P
Y
Q
C
Site 24
Y139
I
H
T
G
E
K
P
Y
Q
C
D
E
C
G
R
Site 25
S149
D
E
C
G
R
C
F
S
Q
S
S
H
L
I
Q
Site 26
T160
H
L
I
Q
H
Q
R
T
H
T
G
E
K
P
Y
Site 27
T162
I
Q
H
Q
R
T
H
T
G
E
K
P
Y
Q
C
Site 28
Y167
T
H
T
G
E
K
P
Y
Q
C
S
E
C
G
K
Site 29
S177
S
E
C
G
K
C
F
S
Q
S
S
H
L
R
Q
Site 30
S180
G
K
C
F
S
Q
S
S
H
L
R
Q
H
M
K
Site 31
T197
K
E
E
K
P
R
K
T
R
G
K
N
I
R
V
Site 32
T206
G
K
N
I
R
V
K
T
H
L
P
S
W
K
A
Site 33
S210
R
V
K
T
H
L
P
S
W
K
A
G
T
G
R
Site 34
T215
L
P
S
W
K
A
G
T
G
R
K
S
V
A
G
Site 35
S219
K
A
G
T
G
R
K
S
V
A
G
L
R
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation