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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HMGA1
Full Name:
High mobility group protein HMG-I/HMG-Y
Alias:
High mobility group AT-hook 1; High mobility group AT-hook protein 1; High mobility group protein A1; High mobility group protein-R; HMG1; HMG3; HMGB1; HMG-I(Y); HMGIY
Type:
DNA binding protein
Mass (Da):
11676
Number AA:
107
UniProt ID:
P17096
International Prot ID:
IPI00179700
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000785
GO:0005829
GO:0005667
Uniprot
OncoNet
Molecular Function:
GO:0003680
GO:0019899
GO:0030374
PhosphoSite+
KinaseNET
Biological Process:
GO:0006268
GO:0019059
GO:0044419
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
E
S
S
S
K
S
S
Site 2
S4
_
_
_
_
M
S
E
S
S
S
K
S
S
Q
P
Site 3
S6
_
_
M
S
E
S
S
S
K
S
S
Q
P
L
A
Site 4
S8
M
S
E
S
S
S
K
S
S
Q
P
L
A
S
K
Site 5
S9
S
E
S
S
S
K
S
S
Q
P
L
A
S
K
Q
Site 6
T21
S
K
Q
E
K
D
G
T
E
K
R
G
R
G
R
Site 7
S36
P
R
K
Q
P
P
V
S
P
G
T
A
L
V
G
Site 8
T39
Q
P
P
V
S
P
G
T
A
L
V
G
S
Q
K
Site 9
S44
P
G
T
A
L
V
G
S
Q
K
E
P
S
E
V
Site 10
S49
V
G
S
Q
K
E
P
S
E
V
P
T
P
K
R
Site 11
T53
K
E
P
S
E
V
P
T
P
K
R
P
R
G
R
Site 12
S64
P
R
G
R
P
K
G
S
K
N
K
G
A
A
K
Site 13
T72
K
N
K
G
A
A
K
T
R
K
T
T
T
T
P
Site 14
T75
A
A
K
T
R
K
T
T
T
T
P
G
R
K
P
Site 15
T76
A
K
T
R
K
T
T
T
T
P
G
R
K
P
R
Site 16
T77
A
K
T
R
K
T
T
T
T
P
G
R
K
P
R
Site 17
T78
K
T
R
K
T
T
T
T
P
G
R
K
P
R
G
Site 18
S99
K
E
E
E
E
G
I
S
Q
E
S
S
E
E
E
Site 19
S102
E
E
G
I
S
Q
E
S
S
E
E
E
Q
_
_
Site 20
S103
E
G
I
S
Q
E
S
S
E
E
E
Q
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation