KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ZNF8
Full Name:
Zinc finger protein 8
Alias:
HF.18; Zfp128; Zinc finger 8
Type:
Mass (Da):
64970
Number AA:
575
UniProt ID:
P17098
International Prot ID:
IPI00419402
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T26
A
R
L
Q
E
P
V
T
F
R
D
V
A
V
D
Site 2
T35
R
D
V
A
V
D
F
T
Q
E
E
W
G
Q
L
Site 3
T45
E
W
G
Q
L
D
P
T
Q
R
I
L
Y
R
D
Site 4
Y50
D
P
T
Q
R
I
L
Y
R
D
V
M
L
E
T
Site 5
S63
E
T
F
G
H
L
L
S
I
G
P
E
L
P
K
Site 6
T90
L
W
V
A
E
R
G
T
T
Q
G
C
H
P
A
Site 7
S102
H
P
A
W
E
P
R
S
E
S
Q
A
S
R
K
Site 8
S104
A
W
E
P
R
S
E
S
Q
A
S
R
K
E
E
Site 9
S107
P
R
S
E
S
Q
A
S
R
K
E
E
G
L
P
Site 10
S119
G
L
P
E
E
E
P
S
H
V
T
G
R
E
G
Site 11
T129
T
G
R
E
G
F
P
T
D
A
P
Y
P
T
T
Site 12
Y133
G
F
P
T
D
A
P
Y
P
T
T
L
G
K
D
Site 13
S145
G
K
D
R
E
C
Q
S
Q
S
L
A
L
K
E
Site 14
S147
D
R
E
C
Q
S
Q
S
L
A
L
K
E
Q
N
Site 15
Y173
A
P
V
Q
D
Q
G
Y
K
T
L
R
L
R
E
Site 16
T175
V
Q
D
Q
G
Y
K
T
L
R
L
R
E
N
C
Site 17
S185
L
R
E
N
C
V
L
S
S
S
P
N
P
F
P
Site 18
S187
E
N
C
V
L
S
S
S
P
N
P
F
P
E
I
Site 19
Y199
P
E
I
S
R
G
E
Y
L
Y
T
Y
D
S
Q
Site 20
Y201
I
S
R
G
E
Y
L
Y
T
Y
D
S
Q
I
T
Site 21
T202
S
R
G
E
Y
L
Y
T
Y
D
S
Q
I
T
D
Site 22
Y203
R
G
E
Y
L
Y
T
Y
D
S
Q
I
T
D
S
Site 23
S205
E
Y
L
Y
T
Y
D
S
Q
I
T
D
S
E
H
Site 24
S210
Y
D
S
Q
I
T
D
S
E
H
N
S
S
L
V
Site 25
S214
I
T
D
S
E
H
N
S
S
L
V
S
Q
Q
T
Site 26
S215
T
D
S
E
H
N
S
S
L
V
S
Q
Q
T
G
Site 27
S218
E
H
N
S
S
L
V
S
Q
Q
T
G
S
P
G
Site 28
T221
S
S
L
V
S
Q
Q
T
G
S
P
G
K
Q
P
Site 29
S223
L
V
S
Q
Q
T
G
S
P
G
K
Q
P
G
E
Site 30
S232
G
K
Q
P
G
E
N
S
D
C
H
R
D
S
S
Site 31
S238
N
S
D
C
H
R
D
S
S
Q
A
I
P
I
T
Site 32
S239
S
D
C
H
R
D
S
S
Q
A
I
P
I
T
E
Site 33
T245
S
S
Q
A
I
P
I
T
E
L
T
K
S
Q
V
Site 34
S250
P
I
T
E
L
T
K
S
Q
V
Q
D
K
P
Y
Site 35
Y257
S
Q
V
Q
D
K
P
Y
K
C
T
D
C
G
K
Site 36
T280
T
V
H
K
R
I
H
T
G
E
R
P
Y
M
C
Site 37
Y285
I
H
T
G
E
R
P
Y
M
C
K
E
C
G
K
Site 38
S295
K
E
C
G
K
A
F
S
Q
N
S
S
L
V
Q
Site 39
S299
K
A
F
S
Q
N
S
S
L
V
Q
H
E
R
I
Site 40
T308
V
Q
H
E
R
I
H
T
G
D
K
P
Y
K
C
Site 41
Y313
I
H
T
G
D
K
P
Y
K
C
A
E
C
G
K
Site 42
T336
T
V
H
R
R
I
H
T
G
E
K
P
Y
E
C
Site 43
Y341
I
H
T
G
E
K
P
Y
E
C
Q
D
C
G
R
Site 44
S354
G
R
A
F
N
Q
N
S
S
L
G
R
H
K
R
Site 45
S355
R
A
F
N
Q
N
S
S
L
G
R
H
K
R
T
Site 46
T362
S
L
G
R
H
K
R
T
H
T
G
E
K
P
Y
Site 47
T364
G
R
H
K
R
T
H
T
G
E
K
P
Y
T
C
Site 48
Y369
T
H
T
G
E
K
P
Y
T
C
S
V
C
G
K
Site 49
T370
H
T
G
E
K
P
Y
T
C
S
V
C
G
K
S
Site 50
S372
G
E
K
P
Y
T
C
S
V
C
G
K
S
F
S
Site 51
S379
S
V
C
G
K
S
F
S
R
T
T
C
L
F
L
Site 52
T382
G
K
S
F
S
R
T
T
C
L
F
L
H
L
R
Site 53
T392
F
L
H
L
R
T
H
T
E
E
R
P
Y
E
C
Site 54
Y397
T
H
T
E
E
R
P
Y
E
C
N
H
C
G
K
Site 55
S409
C
G
K
G
F
R
H
S
S
S
L
A
Q
H
Q
Site 56
S410
G
K
G
F
R
H
S
S
S
L
A
Q
H
Q
R
Site 57
S411
K
G
F
R
H
S
S
S
L
A
Q
H
Q
R
K
Site 58
T436
Q
R
L
I
F
E
Q
T
P
A
L
T
K
H
E
Site 59
S455
L
G
C
D
P
P
L
S
Q
D
E
R
T
H
R
Site 60
T460
P
L
S
Q
D
E
R
T
H
R
S
D
R
P
F
Site 61
S463
Q
D
E
R
T
H
R
S
D
R
P
F
K
C
N
Site 62
T490
I
R
H
Q
I
T
H
T
R
E
E
Q
P
H
G
Site 63
S499
E
E
Q
P
H
G
R
S
R
R
R
E
Q
S
S
Site 64
S505
R
S
R
R
R
E
Q
S
S
S
R
N
S
H
L
Site 65
S506
S
R
R
R
E
Q
S
S
S
R
N
S
H
L
V
Site 66
S507
R
R
R
E
Q
S
S
S
R
N
S
H
L
V
Q
Site 67
S510
E
Q
S
S
S
R
N
S
H
L
V
Q
H
Q
H
Site 68
S520
V
Q
H
Q
H
P
N
S
R
K
S
S
A
G
G
Site 69
S523
Q
H
P
N
S
R
K
S
S
A
G
G
A
K
A
Site 70
S524
H
P
N
S
R
K
S
S
A
G
G
A
K
A
G
Site 71
S535
A
K
A
G
Q
P
E
S
R
A
L
A
L
F
D
Site 72
S566
E
E
P
S
V
G
A
S
M
L
F
D
I
R
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation