PhosphoNET

           
Protein Info 
   
Short Name:  GJA1
Full Name:  Gap junction alpha-1 protein
Alias:  Connexin 43; Connexin-43; CX43; CXA1; CXN-43; Gap junction 43 kDa heart protein; Gap junction protein, alpha 1, 43kDa; GJAL; Oculodentodigital dysplasia (syndactyly type III); ODD; ODDD; ODOD; SDTY3
Type:  Cytoskeletal protein
Mass (Da):  43008
Number AA:  382
UniProt ID:  P17302
International Prot ID:  IPI00218487
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0030660  GO:0005922  GO:0005887 Uniprot OncoNet
Molecular Function:  GO:0015075  GO:0005515  GO:0004871 PhosphoSite+ KinaseNET
Biological Process:  GO:0007267  GO:0016264  GO:0007507 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S5___MGDWSALGKLLD
Site 2Y17LLDKVQAYSTAGGKV
Site 3T56QSAFRCNTQQPGCEN
Site 4Y66PGCENVCYDKSFPIS
Site 5Y98LYLAHVFYVMRKEEK
Site 6Y137IEIKKFKYGIEEHGK
Site 7T186FSLSAVYTCKRDPCP
Site 8S244KDRVKGKSDPYHATS
Site 9Y247VKGKSDPYHATSGAL
Site 10T250KSDPYHATSGALSPA
Site 11S251SDPYHATSGALSPAK
Site 12S255HATSGALSPAKDCGS
Site 13S262SPAKDCGSQKYAYFN
Site 14Y265KDCGSQKYAYFNGCS
Site 15Y267CGSQKYAYFNGCSSP
Site 16S273AYFNGCSSPTAPLSP
Site 17T275FNGCSSPTAPLSPMS
Site 18S279SSPTAPLSPMSPPGY
Site 19S282TAPLSPMSPPGYKLV
Site 20Y286SPMSPPGYKLVTGDR
Site 21T290PPGYKLVTGDRNNSS
Site 22S296VTGDRNNSSCRNYNK
Site 23S297TGDRNNSSCRNYNKQ
Site 24Y301NNSSCRNYNKQASEQ
Site 25S306RNYNKQASEQNWANY
Site 26Y313SEQNWANYSAEQNRM
Site 27S314EQNWANYSAEQNRMG
Site 28S325NRMGQAGSTISNSHA
Site 29T326RMGQAGSTISNSHAQ
Site 30S328GQAGSTISNSHAQPF
Site 31S330AGSTISNSHAQPFDF
Site 32S344FPDDNQNSKKLAAGH
Site 33S364AIVDQRPSSRASSRA
Site 34S365IVDQRPSSRASSRAS
Site 35S368QRPSSRASSRASSRP
Site 36S369RPSSRASSRASSRPR
Site 37S372SRASSRASSRPRPDD
Site 38S373RASSRASSRPRPDDL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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