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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HOXB4
Full Name:
Homeobox protein Hox-B4
Alias:
Homeobox protein Hox-2.6;Homeobox protein Hox-2F
Type:
Mass (Da):
27604
Number AA:
251
UniProt ID:
P17483
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
M
S
S
F
L
I
N
S
N
Y
V
D
P
K
F
Site 2
Y12
S
F
L
I
N
S
N
Y
V
D
P
K
F
P
P
Site 3
S24
F
P
P
C
E
E
Y
S
Q
S
D
Y
L
P
S
Site 4
S26
P
C
E
E
Y
S
Q
S
D
Y
L
P
S
D
H
Site 5
Y28
E
E
Y
S
Q
S
D
Y
L
P
S
D
H
S
P
Site 6
S31
S
Q
S
D
Y
L
P
S
D
H
S
P
G
Y
Y
Site 7
S34
D
Y
L
P
S
D
H
S
P
G
Y
Y
A
G
G
Site 8
Y37
P
S
D
H
S
P
G
Y
Y
A
G
G
Q
R
R
Site 9
Y38
S
D
H
S
P
G
Y
Y
A
G
G
Q
R
R
E
Site 10
S46
A
G
G
Q
R
R
E
S
S
F
Q
P
E
A
G
Site 11
S47
G
G
Q
R
R
E
S
S
F
Q
P
E
A
G
F
Site 12
T61
F
G
R
R
A
A
C
T
V
Q
R
Y
A
A
C
Site 13
S90
P
P
P
P
P
G
L
S
P
R
A
P
A
P
P
Site 14
S114
G
Q
R
C
E
A
V
S
S
S
P
P
P
P
P
Site 15
S115
Q
R
C
E
A
V
S
S
S
P
P
P
P
P
C
Site 16
S116
R
C
E
A
V
S
S
S
P
P
P
P
P
C
A
Site 17
S130
A
Q
N
P
L
H
P
S
P
S
H
S
A
C
K
Site 18
S132
N
P
L
H
P
S
P
S
H
S
A
C
K
E
P
Site 19
S134
L
H
P
S
P
S
H
S
A
C
K
E
P
V
V
Site 20
Y142
A
C
K
E
P
V
V
Y
P
W
M
R
K
V
H
Site 21
T152
M
R
K
V
H
V
S
T
V
N
P
N
Y
A
G
Site 22
Y157
V
S
T
V
N
P
N
Y
A
G
G
E
P
K
R
Site 23
S165
A
G
G
E
P
K
R
S
R
T
A
Y
T
R
Q
Site 24
T167
G
E
P
K
R
S
R
T
A
Y
T
R
Q
Q
V
Site 25
Y169
P
K
R
S
R
T
A
Y
T
R
Q
Q
V
L
E
Site 26
Y183
E
L
E
K
E
F
H
Y
N
R
Y
L
T
R
R
Site 27
Y186
K
E
F
H
Y
N
R
Y
L
T
R
R
R
R
V
Site 28
T188
F
H
Y
N
R
Y
L
T
R
R
R
R
V
E
I
Site 29
T226
K
D
H
K
L
P
N
T
K
I
R
S
G
G
A
Site 30
S230
L
P
N
T
K
I
R
S
G
G
A
A
G
S
A
Site 31
S236
R
S
G
G
A
A
G
S
A
G
G
P
P
G
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation