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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HOXB6
Full Name:
Homeobox protein Hox-B6
Alias:
Homeobox protein Hox-2.2;Homeobox protein Hox-2B;Homeobox protein Hu-2
Type:
Transcription protein
Mass (Da):
25432
Number AA:
224
UniProt ID:
P17509
International Prot ID:
IPI00015075
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0043565
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0008595
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T13
V
N
S
T
F
P
V
T
L
A
S
G
Q
E
S
Site 2
Y28
F
L
G
Q
L
P
L
Y
S
S
G
Y
A
D
P
Site 3
S29
L
G
Q
L
P
L
Y
S
S
G
Y
A
D
P
L
Site 4
S30
G
Q
L
P
L
Y
S
S
G
Y
A
D
P
L
R
Site 5
Y32
L
P
L
Y
S
S
G
Y
A
D
P
L
R
H
Y
Site 6
Y39
Y
A
D
P
L
R
H
Y
P
A
P
Y
G
P
G
Site 7
Y43
L
R
H
Y
P
A
P
Y
G
P
G
P
G
Q
D
Site 8
S57
D
K
G
F
A
T
S
S
Y
Y
P
P
A
G
G
Site 9
Y58
K
G
F
A
T
S
S
Y
Y
P
P
A
G
G
G
Site 10
Y59
G
F
A
T
S
S
Y
Y
P
P
A
G
G
G
Y
Site 11
Y66
Y
P
P
A
G
G
G
Y
G
R
A
A
P
C
D
Site 12
Y74
G
R
A
A
P
C
D
Y
G
P
A
P
A
F
Y
Site 13
Y81
Y
G
P
A
P
A
F
Y
R
E
K
E
S
A
C
Site 14
S86
A
F
Y
R
E
K
E
S
A
C
A
L
S
G
A
Site 15
S106
F
H
P
E
P
R
K
S
D
C
A
Q
D
K
S
Site 16
S113
S
D
C
A
Q
D
K
S
V
F
G
E
T
E
E
Site 17
T125
T
E
E
Q
K
C
S
T
P
V
Y
P
W
M
Q
Site 18
S139
Q
R
M
N
S
C
N
S
S
S
F
G
P
S
G
Site 19
S140
R
M
N
S
C
N
S
S
S
F
G
P
S
G
R
Site 20
S141
M
N
S
C
N
S
S
S
F
G
P
S
G
R
R
Site 21
S145
N
S
S
S
F
G
P
S
G
R
R
G
R
Q
T
Site 22
T152
S
G
R
R
G
R
Q
T
Y
T
R
Y
Q
T
L
Site 23
Y153
G
R
R
G
R
Q
T
Y
T
R
Y
Q
T
L
E
Site 24
Y156
G
R
Q
T
Y
T
R
Y
Q
T
L
E
L
E
K
Site 25
T158
Q
T
Y
T
R
Y
Q
T
L
E
L
E
K
E
F
Site 26
Y167
E
L
E
K
E
F
H
Y
N
R
Y
L
T
R
R
Site 27
Y170
K
E
F
H
Y
N
R
Y
L
T
R
R
R
R
I
Site 28
T172
F
H
Y
N
R
Y
L
T
R
R
R
R
I
E
I
Site 29
S205
R
M
K
W
K
K
E
S
K
L
L
S
A
S
Q
Site 30
S209
K
K
E
S
K
L
L
S
A
S
Q
L
S
A
E
Site 31
S211
E
S
K
L
L
S
A
S
Q
L
S
A
E
E
E
Site 32
S214
L
L
S
A
S
Q
L
S
A
E
E
E
E
E
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation