PhosphoNET

           
Protein Info 
   
Short Name:  TAL1
Full Name:  T-cell acute lymphocytic leukemia protein 1
Alias:  BHLHa17; SCL; Stem cell protein; T-cell acute lymphocytic leukemia 1; T-cell acute lymphocytic leukemia 1 (SCL); T-cell acute lymphocytic leukemia-1 protein; T-cell leukemia/lymphoma-5 protein; TCL5
Type:  Transcription protein
Mass (Da):  34271
Number AA:  331
UniProt ID:  P17542
International Prot ID:  IPI00376954
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634     Uniprot OncoNet
Molecular Function:  GO:0042826  GO:0010843  GO:0003700 PhosphoSite+ KinaseNET
Biological Process:  GO:0045165  GO:0008283  GO:0030218 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S7_MTERPPSEAARSDP
Site 2S12PPSEAARSDPQLEGR
Site 3T90EARHRVPTTELCRPP
Site 4T91ARHRVPTTELCRPPG
Site 5S107APAPAPASVTAELPG
Site 6S122DGRMVQLSPPALAAP
Site 7Y138APGRALLYSLSQPLA
Site 8S139PGRALLYSLSQPLAS
Site 9S141RALLYSLSQPLASLG
Site 10S146SLSQPLASLGSGFFG
Site 11S149QPLASLGSGFFGEPD
Site 12S172NRVKRRPSPYEMEIT
Site 13Y174VKRRPSPYEMEITDG
Site 14T179SPYEMEITDGPHTKV
Site 15T184EITDGPHTKVVRRIF
Site 16T192KVVRRIFTNSRERWR
Site 17S194VRRIFTNSRERWRQQ
Site 18T216ELRKLIPTHPPDKKL
Site 19S224HPPDKKLSKNEILRL
Site 20T251NDQEEEGTQRAKTGK
Site 21T256EGTQRAKTGKDPVVG
Site 22S286DLLQDVLSPNSSCGS
Site 23S289QDVLSPNSSCGSSLD
Site 24S290DVLSPNSSCGSSLDG
Site 25S293SPNSSCGSSLDGAAS
Site 26S294PNSSCGSSLDGAASP
Site 27S300SSLDGAASPDSYTEE
Site 28S303DGAASPDSYTEEPAP
Site 29Y304GAASPDSYTEEPAPK
Site 30T305AASPDSYTEEPAPKH
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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