PhosphoNET

           
Protein Info 
   
Short Name:  SYN1
Full Name:  Synapsin-1
Alias:  Brain protein 4.1; SYN-1; Synapsin I
Type:  Vesicle protein
Mass (Da):  74111
Number AA:  705
UniProt ID:  P17600
International Prot ID:  IPI00300568
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005794  GO:0030054   Uniprot OncoNet
Molecular Function:  GO:0005524  GO:0003779  GO:0003824 PhosphoSite+ KinaseNET
Biological Process:  GO:0007268     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S9NYLRRRLSDSNFMAN
Site 2S11LRRRLSDSNFMANLP
Site 3S39PPPPGAHSPGATPGP
Site 4T43GAHSPGATPGPGTAT
Site 5T50TPGPGTATAERSSGV
Site 6S55TATAERSSGVAPAAS
Site 7S62SGVAPAASPAAPSPG
Site 8S67AASPAAPSPGSSGGG
Site 9S70PAAPSPGSSGGGGFF
Site 10S71AAPSPGSSGGGGFFS
Site 11S78SGGGGFFSSLSNAVK
Site 12S79GGGGFFSSLSNAVKQ
Site 13S81GGFFSSLSNAVKQTT
Site 14S103SEQVGGGSGGAGRGG
Site 15Y129PHTDWAKYFKGKKIH
Site 16S149KVEQAEFSDLNLVAH
Site 17S162AHANGGFSVDMEVLR
Site 18Y198SMARNGDYRSLVIGL
Site 19S200ARNGDYRSLVIGLQY
Site 20S218PSVNSLHSVYNFCDK
Site 21T250EFPLIDQTFYPNHKE
Site 22Y252PLIDQTFYPNHKEML
Site 23S260PNHKEMLSSTTYPVV
Site 24S261NHKEMLSSTTYPVVV
Site 25T262HKEMLSSTTYPVVVK
Site 26S275VKMGHAHSGMGKVKV
Site 27Y301VVALTKTYATAEPFI
Site 28Y312EPFIDAKYDVRVQKI
Site 29Y326IGQNYKAYMRTSVSG
Site 30S332AYMRTSVSGNWKTNT
Site 31T337SVSGNWKTNTGSAML
Site 32T339SGNWKTNTGSAMLEQ
Site 33S341NWKTNTGSAMLEQIA
Site 34Y353QIAMSDRYKLWVDTC
Site 35S390HIIEVVGSSMPLIGD
Site 36S391IIEVVGSSMPLIGDH
Site 37S427RQRQRDASPGRGSHG
Site 38S432DASPGRGSHGQTPSP
Site 39T436GRGSHGQTPSPGALP
Site 40S438GSHGQTPSPGALPLG
Site 41T448ALPLGRQTSQQPAGP
Site 42S449LPLGRQTSQQPAGPP
Site 43S494PQGQQHLSGLGPPAG
Site 44S502GLGPPAGSPLPQRLP
Site 45S510PLPQRLPSPTSAPQQ
Site 46T512PQRLPSPTSAPQQPA
Site 47S513QRLPSPTSAPQQPAS
Site 48S520SAPQQPASQAAPPTQ
Site 49S533TQGQGRQSRPVAGGP
Site 50S551PAARPPASPSPQRQA
Site 51S553ARPPASPSPQRQAGP
Site 52T567PPQATRQTSVSGPAP
Site 53S568PQATRQTSVSGPAPP
Site 54S570ATRQTSVSGPAPPKA
Site 55S578GPAPPKASGAPPGGQ
Site 56S605AGPTRQASQAGPVPR
Site 57T613QAGPVPRTGPPTTQQ
Site 58T617VPRTGPPTTQQPRPS
Site 59T618PRTGPPTTQQPRPSG
Site 60S624TTQQPRPSGPGPAGR
Site 61S641PQLAQKPSQDVPPPA
Site 62S663PHPQLNKSQSLTNAF
Site 63S665PQLNKSQSLTNAFNL
Site 64T667LNKSQSLTNAFNLPE
Site 65S681EPAPPRPSLSQDEVK
Site 66S683APPRPSLSQDEVKAE
Site 67T691QDEVKAETIRSLRKS
Site 68S694VKAETIRSLRKSFAS
Site 69S698TIRSLRKSFASLFSD
Site 70S701SLRKSFASLFSD___
Site 71S704KSFASLFSD______
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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