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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BMP7
Full Name:
Bone morphogenetic protein 7
Alias:
Osteogenic protein 1
Type:
Mass (Da):
49313
Number AA:
431
UniProt ID:
P18075
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S32
R
S
A
L
A
D
F
S
L
D
N
E
V
H
S
Site 2
S40
L
D
N
E
V
H
S
S
F
I
H
R
R
L
R
Site 3
S48
F
I
H
R
R
L
R
S
Q
E
R
R
E
M
Q
Site 4
S60
E
M
Q
R
E
I
L
S
I
L
G
L
P
H
R
Site 5
S104
G
P
G
G
Q
G
F
S
Y
P
Y
K
A
V
F
Site 6
Y105
P
G
G
Q
G
F
S
Y
P
Y
K
A
V
F
S
Site 7
Y107
G
Q
G
F
S
Y
P
Y
K
A
V
F
S
T
Q
Site 8
T113
P
Y
K
A
V
F
S
T
Q
G
P
P
L
A
S
Site 9
S120
T
Q
G
P
P
L
A
S
L
Q
D
S
H
F
L
Site 10
S124
P
L
A
S
L
Q
D
S
H
F
L
T
D
A
D
Site 11
T128
L
Q
D
S
H
F
L
T
D
A
D
M
V
M
S
Site 12
Y151
K
E
F
F
H
P
R
Y
H
H
R
E
F
R
F
Site 13
S161
R
E
F
R
F
D
L
S
K
I
P
E
G
E
A
Site 14
Y177
T
A
A
E
F
R
I
Y
K
D
Y
I
R
E
R
Site 15
Y180
E
F
R
I
Y
K
D
Y
I
R
E
R
F
D
N
Site 16
T189
R
E
R
F
D
N
E
T
F
R
I
S
V
Y
Q
Site 17
S193
D
N
E
T
F
R
I
S
V
Y
Q
V
L
Q
E
Site 18
Y195
E
T
F
R
I
S
V
Y
Q
V
L
Q
E
H
L
Site 19
S206
Q
E
H
L
G
R
E
S
D
L
F
L
L
D
S
Site 20
S213
S
D
L
F
L
L
D
S
R
T
L
W
A
S
E
Site 21
T215
L
F
L
L
D
S
R
T
L
W
A
S
E
E
G
Site 22
S219
D
S
R
T
L
W
A
S
E
E
G
W
L
V
F
Site 23
S248
H
N
L
G
L
Q
L
S
V
E
T
L
D
G
Q
Site 24
S256
V
E
T
L
D
G
Q
S
I
N
P
K
L
A
G
Site 25
S290
A
T
E
V
H
F
R
S
I
R
S
T
G
S
K
Site 26
S293
V
H
F
R
S
I
R
S
T
G
S
K
Q
R
S
Site 27
T294
H
F
R
S
I
R
S
T
G
S
K
Q
R
S
Q
Site 28
S296
R
S
I
R
S
T
G
S
K
Q
R
S
Q
N
R
Site 29
S300
S
T
G
S
K
Q
R
S
Q
N
R
S
K
T
P
Site 30
S304
K
Q
R
S
Q
N
R
S
K
T
P
K
N
Q
E
Site 31
T306
R
S
Q
N
R
S
K
T
P
K
N
Q
E
A
L
Site 32
S322
M
A
N
V
A
E
N
S
S
S
D
Q
R
Q
A
Site 33
S323
A
N
V
A
E
N
S
S
S
D
Q
R
Q
A
C
Site 34
S324
N
V
A
E
N
S
S
S
D
Q
R
Q
A
C
K
Site 35
Y336
A
C
K
K
H
E
L
Y
V
S
F
R
D
L
G
Site 36
S338
K
K
H
E
L
Y
V
S
F
R
D
L
G
W
Q
Site 37
Y357
A
P
E
G
Y
A
A
Y
Y
C
E
G
E
C
A
Site 38
Y358
P
E
G
Y
A
A
Y
Y
C
E
G
E
C
A
F
Site 39
S405
P
T
Q
L
N
A
I
S
V
L
Y
F
D
D
S
Site 40
S412
S
V
L
Y
F
D
D
S
S
N
V
I
L
K
K
Site 41
S413
V
L
Y
F
D
D
S
S
N
V
I
L
K
K
Y
Site 42
Y420
S
N
V
I
L
K
K
Y
R
N
M
V
V
R
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation