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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ADCYAP1
Full Name:
Pituitary adenylate cyclase-activating polypeptide
Alias:
Adenylate cyclase activating polypeptide 1 (pituitary); PACA; PACAP; PACAP-related peptide; Pituitary adenylate cyclase-activating polypeptide 27; Pituitary adenylate cyclase-activating polypeptide 38; PRP-48
Type:
Secreted protein
Mass (Da):
18835
Number AA:
176
UniProt ID:
P18509
International Prot ID:
IPI00000027
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
GO:0005625
Uniprot
OncoNet
Molecular Function:
GO:0005184
PhosphoSite+
KinaseNET
Biological Process:
GO:0007186
GO:0007190
GO:0007267
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S25
M
H
S
S
V
Y
S
S
P
A
A
A
G
L
R
Site 2
Y43
I
R
P
E
E
E
A
Y
G
E
D
G
N
P
L
Site 3
S56
P
L
P
D
F
D
G
S
E
P
P
G
A
G
S
Site 4
S63
S
E
P
P
G
A
G
S
P
A
S
A
P
R
A
Site 5
S66
P
G
A
G
S
P
A
S
A
P
R
A
A
A
A
Site 6
Y92
H
G
I
L
N
E
A
Y
R
K
V
L
D
Q
L
Site 7
S100
R
K
V
L
D
Q
L
S
A
G
K
H
L
Q
S
Site 8
S107
S
A
G
K
H
L
Q
S
L
V
A
R
G
V
G
Site 9
S129
G
D
D
A
E
P
L
S
K
R
H
S
D
G
I
Site 10
S133
E
P
L
S
K
R
H
S
D
G
I
F
T
D
S
Site 11
T138
R
H
S
D
G
I
F
T
D
S
Y
S
R
Y
R
Site 12
S140
S
D
G
I
F
T
D
S
Y
S
R
Y
R
K
Q
Site 13
Y141
D
G
I
F
T
D
S
Y
S
R
Y
R
K
Q
M
Site 14
S142
G
I
F
T
D
S
Y
S
R
Y
R
K
Q
M
A
Site 15
Y144
F
T
D
S
Y
S
R
Y
R
K
Q
M
A
V
K
Site 16
Y153
K
Q
M
A
V
K
K
Y
L
A
A
V
L
G
K
Site 17
Y162
A
A
V
L
G
K
R
Y
K
Q
R
V
K
N
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation