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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
K15
Full Name:
Keratin, type I cytoskeletal 15
Alias:
CK15; CK-15; Cytokeratin 15; Cytokeratin-15; K1C15; K1CO; Keratin 15; Keratin-15; Keratin-15, basic; Keratin-15, beta; KRT15; KRTB; Type I cytoskeletal 15
Type:
Cytoskeletal protein
Mass (Da):
49198
Number AA:
456
UniProt ID:
P19012
International Prot ID:
IPI00290077
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005882
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005200
PhosphoSite+
KinaseNET
Biological Process:
GO:0008544
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
T
T
T
F
L
Q
T
S
S
S
T
F
G
G
G
Site 2
S10
T
T
F
L
Q
T
S
S
S
T
F
G
G
G
S
Site 3
S11
T
F
L
Q
T
S
S
S
T
F
G
G
G
S
T
Site 4
T12
F
L
Q
T
S
S
S
T
F
G
G
G
S
T
R
Site 5
S17
S
S
T
F
G
G
G
S
T
R
G
G
S
L
L
Site 6
T18
S
T
F
G
G
G
S
T
R
G
G
S
L
L
A
Site 7
S22
G
G
S
T
R
G
G
S
L
L
A
G
G
G
G
Site 8
S34
G
G
G
F
G
G
G
S
L
S
G
G
G
G
S
Site 9
S36
G
F
G
G
G
S
L
S
G
G
G
G
S
R
S
Site 10
S41
S
L
S
G
G
G
G
S
R
S
I
S
A
S
S
Site 11
S43
S
G
G
G
G
S
R
S
I
S
A
S
S
A
R
Site 12
S45
G
G
G
S
R
S
I
S
A
S
S
A
R
F
V
Site 13
S47
G
S
R
S
I
S
A
S
S
A
R
F
V
S
S
Site 14
S48
S
R
S
I
S
A
S
S
A
R
F
V
S
S
G
Site 15
S53
A
S
S
A
R
F
V
S
S
G
S
G
G
G
Y
Site 16
S54
S
S
A
R
F
V
S
S
G
S
G
G
G
Y
G
Site 17
S56
A
R
F
V
S
S
G
S
G
G
G
Y
G
G
G
Site 18
Y60
S
S
G
S
G
G
G
Y
G
G
G
M
R
V
C
Site 19
S102
G
G
D
G
G
L
L
S
G
N
E
K
I
T
M
Site 20
S118
N
L
N
D
R
L
A
S
Y
L
D
K
V
R
A
Site 21
Y119
L
N
D
R
L
A
S
Y
L
D
K
V
R
A
L
Site 22
Y141
E
V
K
I
H
D
W
Y
Q
K
Q
T
P
T
S
Site 23
T145
H
D
W
Y
Q
K
Q
T
P
T
S
P
E
C
D
Site 24
S148
Y
Q
K
Q
T
P
T
S
P
E
C
D
Y
S
Q
Site 25
Y153
P
T
S
P
E
C
D
Y
S
Q
Y
F
K
T
I
Site 26
S154
T
S
P
E
C
D
Y
S
Q
Y
F
K
T
I
E
Site 27
Y156
P
E
C
D
Y
S
Q
Y
F
K
T
I
E
E
L
Site 28
Y195
A
D
D
F
R
L
K
Y
E
N
E
L
A
L
R
Site 29
T220
R
R
V
L
D
E
L
T
L
A
R
T
D
L
E
Site 30
Y239
G
L
N
E
E
L
A
Y
L
K
K
N
H
E
E
Site 31
S253
E
E
M
K
E
F
S
S
Q
L
A
G
Q
V
N
Site 32
Y282
L
A
E
M
R
E
Q
Y
E
A
M
A
E
K
N
Site 33
T301
E
A
W
F
F
S
K
T
E
E
L
N
K
E
V
Site 34
S310
E
L
N
K
E
V
A
S
N
T
E
M
I
Q
T
Site 35
T312
N
K
E
V
A
S
N
T
E
M
I
Q
T
S
K
Site 36
T317
S
N
T
E
M
I
Q
T
S
K
T
E
I
T
D
Site 37
S318
N
T
E
M
I
Q
T
S
K
T
E
I
T
D
L
Site 38
T320
E
M
I
Q
T
S
K
T
E
I
T
D
L
R
R
Site 39
T323
Q
T
S
K
T
E
I
T
D
L
R
R
T
M
Q
Site 40
T328
E
I
T
D
L
R
R
T
M
Q
E
L
E
I
E
Site 41
S341
I
E
L
Q
S
Q
L
S
M
K
A
G
L
E
N
Site 42
S349
M
K
A
G
L
E
N
S
L
A
E
T
E
C
R
Site 43
T353
L
E
N
S
L
A
E
T
E
C
R
Y
A
T
Q
Site 44
T359
E
T
E
C
R
Y
A
T
Q
L
Q
Q
I
Q
G
Site 45
S376
G
G
L
E
A
Q
L
S
E
L
R
C
E
M
E
Site 46
Y389
M
E
A
Q
N
Q
E
Y
K
M
L
L
D
I
K
Site 47
T397
K
M
L
L
D
I
K
T
R
L
E
Q
E
I
A
Site 48
Y406
L
E
Q
E
I
A
T
Y
R
S
L
L
E
G
Q
Site 49
S426
G
I
G
I
R
E
A
S
S
G
G
G
G
S
S
Site 50
S427
I
G
I
R
E
A
S
S
G
G
G
G
S
S
S
Site 51
S432
A
S
S
G
G
G
G
S
S
S
N
F
H
I
N
Site 52
S433
S
S
G
G
G
G
S
S
S
N
F
H
I
N
V
Site 53
S434
S
G
G
G
G
S
S
S
N
F
H
I
N
V
E
Site 54
S450
S
V
D
G
Q
V
V
S
S
H
K
R
E
I
_
Site 55
S451
V
D
G
Q
V
V
S
S
H
K
R
E
I
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation