PhosphoNET

           
Protein Info 
   
Short Name:  CYP11B2
Full Name:  Cytochrome P450 11B2, mitochondrial
Alias:  Aldosterone synthase;Aldosterone-synthesizing enzyme;CYPXIB2;Cytochrome P-450Aldo;Cytochrome P-450C18;Steroid 18-hydroxylase
Type: 
Mass (Da):  57560
Number AA:  503
UniProt ID:  P19099
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T34RAARAPRTVLPFEAM
Site 2T71LHLEMHQTFQELGPI
Site 3Y81ELGPIFRYNLGGPRM
Site 4S105EKLQQVDSLHPCRMI
Site 5Y119ILEPWVAYRQHRGHK
Site 6S150RLNPDVLSPKAVQRF
Site 7S169DAVARDFSQALKKKV
Site 8S183VLQNARGSLTLDVQP
Site 9T185QNARGSLTLDVQPSI
Site 10T196QPSIFHYTIEASNLA
Site 11S215RLGLVGHSPSSASLN
Site 12S220GHSPSSASLNFLHAL
Site 13S243QLMFMPRSLSRWISP
Site 14S245MFMPRSLSRWISPKV
Site 15S249RSLSRWISPKVWKEH
Site 16Y275DNCIQKIYQELAFNR
Site 17T287FNRPQHYTGIVAELL
Site 18T312KANSMELTAGSVDTT
Site 19S350ESLAAAASISEHPQK
Site 20S352LAAAASISEHPQKAT
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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