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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
UGT1A6
Full Name:
UDP-glucuronosyltransferase 1-6
Alias:
Phenol-metabolizing UDP-glucuronosyltransferase;UDP-glucuronosyltransferase 1-F;UDP-glucuronosyltransferase 1A6
Type:
Mass (Da):
60751
Number AA:
532
UniProt ID:
P19224
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S37
L
V
V
P
Q
D
G
S
H
W
L
S
M
K
D
Site 2
S41
Q
D
G
S
H
W
L
S
M
K
D
I
V
E
V
Site 3
S50
K
D
I
V
E
V
L
S
D
R
G
H
E
I
V
Site 4
Y72
L
L
L
K
E
S
K
Y
Y
T
R
K
I
Y
P
Site 5
Y73
L
L
K
E
S
K
Y
Y
T
R
K
I
Y
P
V
Site 6
T74
L
K
E
S
K
Y
Y
T
R
K
I
Y
P
V
P
Site 7
Y78
K
Y
Y
T
R
K
I
Y
P
V
P
Y
D
Q
E
Site 8
Y82
R
K
I
Y
P
V
P
Y
D
Q
E
E
L
K
N
Site 9
Y91
Q
E
E
L
K
N
R
Y
Q
S
F
G
N
N
H
Site 10
S93
E
L
K
N
R
Y
Q
S
F
G
N
N
H
F
A
Site 11
S103
N
N
H
F
A
E
R
S
F
L
T
A
P
Q
T
Site 12
T110
S
F
L
T
A
P
Q
T
E
Y
R
N
N
M
I
Site 13
T135
S
L
L
Q
D
R
D
T
L
N
F
F
K
E
S
Site 14
S177
L
F
R
G
F
P
C
S
L
E
H
T
F
S
R
Site 15
T181
F
P
C
S
L
E
H
T
F
S
R
S
P
D
P
Site 16
S183
C
S
L
E
H
T
F
S
R
S
P
D
P
V
S
Site 17
S185
L
E
H
T
F
S
R
S
P
D
P
V
S
Y
I
Site 18
S190
S
R
S
P
D
P
V
S
Y
I
P
R
C
Y
T
Site 19
Y191
R
S
P
D
P
V
S
Y
I
P
R
C
Y
T
K
Site 20
Y196
V
S
Y
I
P
R
C
Y
T
K
F
S
D
H
M
Site 21
T204
T
K
F
S
D
H
M
T
F
S
Q
R
V
A
N
Site 22
Y220
L
V
N
L
L
E
P
Y
L
F
Y
C
L
F
S
Site 23
Y223
L
L
E
P
Y
L
F
Y
C
L
F
S
K
Y
E
Site 24
S227
Y
L
F
Y
C
L
F
S
K
Y
E
E
L
A
S
Site 25
Y229
F
Y
C
L
F
S
K
Y
E
E
L
A
S
A
V
Site 26
T245
K
R
D
V
D
I
I
T
L
Y
Q
K
V
S
V
Site 27
Y263
R
Y
D
F
V
L
E
Y
P
R
P
V
M
P
N
Site 28
S286
C
K
K
R
K
D
L
S
Q
E
F
E
A
Y
I
Site 29
Y292
L
S
Q
E
F
E
A
Y
I
N
A
S
G
E
H
Site 30
S311
F
S
L
G
S
M
V
S
E
I
P
E
K
K
A
Site 31
T331
A
L
G
K
I
P
Q
T
V
L
W
R
Y
T
G
Site 32
Y336
P
Q
T
V
L
W
R
Y
T
G
T
R
P
S
N
Site 33
T337
Q
T
V
L
W
R
Y
T
G
T
R
P
S
N
L
Site 34
S342
R
Y
T
G
T
R
P
S
N
L
A
N
N
T
I
Site 35
Y378
H
A
G
S
H
G
V
Y
E
S
I
C
N
G
V
Site 36
T405
D
N
A
K
R
M
E
T
K
G
A
G
V
T
L
Site 37
S434
K
A
V
I
N
D
K
S
Y
K
E
N
I
M
R
Site 38
Y435
A
V
I
N
D
K
S
Y
K
E
N
I
M
R
L
Site 39
S443
K
E
N
I
M
R
L
S
S
L
H
K
D
R
P
Site 40
S444
E
N
I
M
R
L
S
S
L
H
K
D
R
P
V
Site 41
Y483
A
A
H
D
L
T
W
Y
Q
Y
H
S
L
D
V
Site 42
Y485
H
D
L
T
W
Y
Q
Y
H
S
L
D
V
I
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation