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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Elk-1
Full Name:
ETS domain-containing protein Elk-1
Alias:
ELK1; ELK1, member of ETS oncogene family; ETS-domain protein Elk-1; ETS-domain protein ELK-1
Type:
Transcription protein
Mass (Da):
44888
Number AA:
428
UniProt ID:
P19419
International Prot ID:
IPI00301527
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0043565
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0045944
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S25
Q
G
N
G
H
I
I
S
W
T
S
R
D
G
G
Site 2
T27
N
G
H
I
I
S
W
T
S
R
D
G
G
E
F
Site 3
Y57
K
N
K
T
N
M
N
Y
D
K
L
S
R
A
L
Site 4
Y67
L
S
R
A
L
R
Y
Y
Y
D
K
N
I
I
R
Site 5
Y68
S
R
A
L
R
Y
Y
Y
D
K
N
I
I
R
K
Site 6
S77
K
N
I
I
R
K
V
S
G
Q
K
F
V
Y
K
Site 7
Y83
V
S
G
Q
K
F
V
Y
K
F
V
S
Y
P
E
Site 8
S106
C
P
P
Q
P
E
V
S
V
T
S
T
M
P
N
Site 9
T108
P
Q
P
E
V
S
V
T
S
T
M
P
N
V
A
Site 10
T126
I
H
A
A
P
G
D
T
V
S
G
K
P
G
T
Site 11
S128
A
A
P
G
D
T
V
S
G
K
P
G
T
P
K
Site 12
T133
T
V
S
G
K
P
G
T
P
K
G
A
G
M
A
Site 13
S148
G
P
G
G
L
A
R
S
S
R
N
E
Y
M
R
Site 14
S149
P
G
G
L
A
R
S
S
R
N
E
Y
M
R
S
Site 15
Y153
A
R
S
S
R
N
E
Y
M
R
S
G
L
Y
S
Site 16
S156
S
R
N
E
Y
M
R
S
G
L
Y
S
T
F
T
Site 17
S160
Y
M
R
S
G
L
Y
S
T
F
T
I
Q
S
L
Site 18
T161
M
R
S
G
L
Y
S
T
F
T
I
Q
S
L
Q
Site 19
T163
S
G
L
Y
S
T
F
T
I
Q
S
L
Q
P
Q
Site 20
S166
Y
S
T
F
T
I
Q
S
L
Q
P
Q
P
P
P
Site 21
S194
A
G
A
A
A
P
P
S
G
S
R
S
T
S
P
Site 22
S196
A
A
A
P
P
S
G
S
R
S
T
S
P
S
P
Site 23
S198
A
P
P
S
G
S
R
S
T
S
P
S
P
L
E
Site 24
T199
P
P
S
G
S
R
S
T
S
P
S
P
L
E
A
Site 25
S200
P
S
G
S
R
S
T
S
P
S
P
L
E
A
C
Site 26
S202
G
S
R
S
T
S
P
S
P
L
E
A
C
L
E
Site 27
T269
E
R
G
F
V
P
E
T
T
K
A
E
P
E
V
Site 28
S303
Q
A
G
G
H
A
A
S
S
P
E
I
S
Q
P
Site 29
S304
A
G
G
H
A
A
S
S
P
E
I
S
Q
P
Q
Site 30
S308
A
A
S
S
P
E
I
S
Q
P
Q
K
G
R
K
Site 31
S324
R
D
L
E
L
P
L
S
P
S
L
L
G
G
P
Site 32
S326
L
E
L
P
L
S
P
S
L
L
G
G
P
G
P
Site 33
T336
G
G
P
G
P
E
R
T
P
G
S
G
S
G
S
Site 34
S339
G
P
E
R
T
P
G
S
G
S
G
S
G
L
Q
Site 35
S341
E
R
T
P
G
S
G
S
G
S
G
L
Q
A
P
Site 36
S343
T
P
G
S
G
S
G
S
G
L
Q
A
P
G
P
Site 37
T353
Q
A
P
G
P
A
L
T
P
S
L
L
P
T
H
Site 38
T363
L
L
P
T
H
T
L
T
P
V
L
L
T
P
S
Site 39
T368
T
L
T
P
V
L
L
T
P
S
S
L
P
P
S
Site 40
S375
T
P
S
S
L
P
P
S
I
H
F
W
S
T
L
Site 41
T381
P
S
I
H
F
W
S
T
L
S
P
I
A
P
R
Site 42
S383
I
H
F
W
S
T
L
S
P
I
A
P
R
S
P
Site 43
S389
L
S
P
I
A
P
R
S
P
A
K
L
S
F
Q
Site 44
S394
P
R
S
P
A
K
L
S
F
Q
F
P
S
S
G
Site 45
S411
Q
V
H
I
P
S
I
S
V
D
G
L
S
T
P
Site 46
S416
S
I
S
V
D
G
L
S
T
P
V
V
L
S
P
Site 47
T417
I
S
V
D
G
L
S
T
P
V
V
L
S
P
G
Site 48
S422
L
S
T
P
V
V
L
S
P
G
P
Q
K
P
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation