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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TNNI3
Full Name:
Troponin I, cardiac muscle
Alias:
CMH7; TNNC1; Troponin I type 3 (cardiac)
Type:
Actin binding protein; Motor protein
Mass (Da):
24008
Number AA:
210
UniProt ID:
P19429
International Prot ID:
IPI00244346
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005861
Uniprot
OncoNet
Molecular Function:
GO:0003779
GO:0019855
GO:0048306
PhosphoSite+
KinaseNET
Biological Process:
GO:0060048
GO:0006874
GO:0032780
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
A
D
G
S
S
D
A
A
R
E
P
R
Site 2
S23
P
A
P
I
R
R
R
S
S
N
Y
R
A
Y
A
Site 3
S24
A
P
I
R
R
R
S
S
N
Y
R
A
Y
A
T
Site 4
Y26
I
R
R
R
S
S
N
Y
R
A
Y
A
T
E
P
Site 5
Y29
R
S
S
N
Y
R
A
Y
A
T
E
P
H
A
K
Site 6
T31
S
N
Y
R
A
Y
A
T
E
P
H
A
K
K
K
Site 7
S39
E
P
H
A
K
K
K
S
K
I
S
A
S
R
K
Site 8
S42
A
K
K
K
S
K
I
S
A
S
R
K
L
Q
L
Site 9
S44
K
K
S
K
I
S
A
S
R
K
L
Q
L
K
T
Site 10
T51
S
R
K
L
Q
L
K
T
L
L
L
Q
I
A
K
Site 11
S77
G
E
K
G
R
A
L
S
T
R
C
Q
P
L
E
Site 12
T78
E
K
G
R
A
L
S
T
R
C
Q
P
L
E
L
Site 13
Y112
D
K
V
D
E
E
R
Y
D
I
E
A
K
V
T
Site 14
T119
Y
D
I
E
A
K
V
T
K
N
I
T
E
I
A
Site 15
T129
I
T
E
I
A
D
L
T
Q
K
I
F
D
L
R
Site 16
T143
R
G
K
F
K
R
P
T
L
R
R
V
R
I
S
Site 17
S150
T
L
R
R
V
R
I
S
A
D
A
M
M
Q
A
Site 18
S166
L
G
A
R
A
K
E
S
L
D
L
R
A
H
L
Site 19
S199
R
K
N
I
D
A
L
S
G
M
E
G
R
K
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation