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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
p67phox
Full Name:
Neutrophil cytosol factor 2
Alias:
67 kDa neutrophil oxidase factor; Chronic granulomatous disease, autosomal 2; NADPH oxidase activator 2; NCF2; NCF-2; Neutrophil cytosolic factor 2; Neutrophil NADPH oxidase factor 2; NOXA2; P67phox; P67-phox
Type:
Enzyme, oxidoreductase
Mass (Da):
59762
Number AA:
526
UniProt ID:
P19878
International Prot ID:
IPI00021070
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0043020
GO:0005737
GO:0005730
Uniprot
OncoNet
Molecular Function:
GO:0009055
GO:0008022
PhosphoSite+
KinaseNET
Biological Process:
GO:0006968
GO:0045087
GO:0045730
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S30
K
G
A
L
D
A
F
S
A
V
Q
D
P
H
S
Site 2
T61
T
E
A
E
K
A
F
T
R
S
I
N
R
D
K
Site 3
S63
A
E
K
A
F
T
R
S
I
N
R
D
K
H
L
Site 4
Y74
D
K
H
L
A
V
A
Y
F
Q
R
G
M
L
Y
Site 5
Y81
Y
F
Q
R
G
M
L
Y
Y
Q
T
E
K
Y
D
Site 6
Y82
F
Q
R
G
M
L
Y
Y
Q
T
E
K
Y
D
L
Site 7
Y87
L
Y
Y
Q
T
E
K
Y
D
L
A
I
K
D
L
Site 8
Y109
R
G
N
Q
L
I
D
Y
K
I
L
G
L
Q
F
Site 9
Y131
L
Y
N
I
A
F
M
Y
A
K
K
E
E
W
K
Site 10
S149
E
Q
L
A
L
A
T
S
M
K
S
E
P
R
H
Site 11
S152
A
L
A
T
S
M
K
S
E
P
R
H
S
K
I
Site 12
S157
M
K
S
E
P
R
H
S
K
I
D
K
A
M
E
Site 13
Y198
A
Q
L
A
K
K
D
Y
L
G
K
A
T
V
V
Site 14
S215
V
V
D
Q
D
S
F
S
G
F
A
P
L
Q
P
Site 15
T233
E
P
P
P
R
P
K
T
P
E
I
F
R
A
L
Site 16
Y293
K
G
L
V
P
C
N
Y
L
E
P
V
E
L
R
Site 17
S311
Q
Q
Q
P
Q
E
E
S
S
P
Q
S
D
I
P
Site 18
S312
Q
Q
P
Q
E
E
S
S
P
Q
S
D
I
P
A
Site 19
S315
Q
E
E
S
S
P
Q
S
D
I
P
A
P
P
S
Site 20
S322
S
D
I
P
A
P
P
S
S
K
A
P
G
R
P
Site 21
S323
D
I
P
A
P
P
S
S
K
A
P
G
R
P
Q
Site 22
S332
A
P
G
R
P
Q
L
S
P
G
Q
K
Q
K
E
Site 23
S347
E
P
K
E
V
K
L
S
V
P
M
P
Y
T
L
Site 24
Y352
K
L
S
V
P
M
P
Y
T
L
K
V
H
Y
K
Site 25
T353
L
S
V
P
M
P
Y
T
L
K
V
H
Y
K
Y
Site 26
Y360
T
L
K
V
H
Y
K
Y
T
V
V
M
K
T
Q
Site 27
T366
K
Y
T
V
V
M
K
T
Q
P
G
L
P
Y
S
Site 28
S373
T
Q
P
G
L
P
Y
S
Q
V
R
D
M
V
S
Site 29
S393
R
L
E
H
T
K
L
S
Y
R
P
R
D
S
N
Site 30
S399
L
S
Y
R
P
R
D
S
N
E
L
V
P
L
S
Site 31
S406
S
N
E
L
V
P
L
S
E
D
S
M
K
D
A
Site 32
T451
K
A
D
A
N
N
Q
T
T
E
P
Q
L
K
K
Site 33
S460
E
P
Q
L
K
K
G
S
Q
V
E
A
L
F
S
Site 34
S467
S
Q
V
E
A
L
F
S
Y
E
A
T
Q
P
E
Site 35
Y468
Q
V
E
A
L
F
S
Y
E
A
T
Q
P
E
D
Site 36
T471
A
L
F
S
Y
E
A
T
Q
P
E
D
L
E
F
Site 37
T516
V
F
V
E
D
C
A
T
T
D
L
E
S
T
R
Site 38
S521
C
A
T
T
D
L
E
S
T
R
R
E
V
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation