PhosphoNET

           
Protein Info 
   
Short Name:  FST
Full Name:  Follistatin
Alias:  Activin-binding protein
Type: 
Mass (Da):  38007
Number AA:  344
UniProt ID:  P19883
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y46NGRCQVLYKTELSKE
Site 2T48RCQVLYKTELSKEEC
Site 3S51VLYKTELSKEECCST
Site 4S57LSKEECCSTGRLSTS
Site 5T58SKEECCSTGRLSTSW
Site 6S62CCSTGRLSTSWTEED
Site 7T63CSTGRLSTSWTEEDV
Site 8S64STGRLSTSWTEEDVN
Site 9T66GRLSTSWTEEDVNDN
Site 10T138VCGLDGKTYRNECAL
Site 11Y139CGLDGKTYRNECALL
Site 12S176RDVFCPGSSTCVVDQ
Site 13S201RICPEPASSEQYLCG
Site 14S202ICPEPASSEQYLCGN
Site 15Y205EPASSEQYLCGNDGV
Site 16Y214CGNDGVTYSSACHLR
Site 17S215GNDGVTYSSACHLRK
Site 18S216NDGVTYSSACHLRKA
Site 19S268KVGRGRCSLCDELCP
Site 20S277CDELCPDSKSDEPVC
Site 21S279ELCPDSKSDEPVCAS
Site 22S286SDEPVCASDNATYAS
Site 23S293SDNATYASECAMKEA
Site 24S315LEVKHSGSCNSISED
Site 25S318KHSGSCNSISEDTEE
Site 26S320SGSCNSISEDTEEEE
Site 27Y334EEDEDQDYSFPISSI
Site 28S335EDEDQDYSFPISSIL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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