PhosphoNET

           
Protein Info 
   
Short Name:  TYMP
Full Name:  Thymidine phosphorylase
Alias:  TdRPase
Type: 
Mass (Da):  49937
Number AA:  482
UniProt ID:  P19971
International Prot ID:  IPI00292858
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005829  GO:0043226  GO:0043227 Uniprot OncoNet
Molecular Function:  GO:0003824  GO:0005102  GO:0005125 PhosphoSite+ KinaseNET
Biological Process:  GO:0000002  GO:0001525  GO:0006139 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S19PPAPGDFSGEGSQGL
Site 2S23GDFSGEGSQGLPDPS
Site 3S30SQGLPDPSPEPKQLP
Site 4S50KRDGGRLSEADIRGF
Site 5S117QQLVDKHSTGGVGDK
Site 6S144GCKVPMISGRGLGHT
Site 7T151SGRGLGHTGGTLDKL
Site 8S169PGFNVIQSPEQMQVL
Site 9T271LRVAAALTAMDKPLG
Site 10S362GLARALCSGSPAERR
Site 11S364ARALCSGSPAERRQL
Site 12S409HELGAGRSRAGEPLR
Site 13T435GQRLRRGTPWLRVHR
Site 14S448HRDGPALSGPQSRAL
Site 15S452PALSGPQSRALQEAL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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