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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PGC
Full Name:
Gastricsin
Alias:
Pepsinogen C
Type:
Mass (Da):
42426
Number AA:
388
UniProt ID:
P20142
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S28
V
P
L
K
K
F
K
S
I
R
E
T
M
K
E
Site 2
T32
K
F
K
S
I
R
E
T
M
K
E
K
G
L
L
Site 3
T45
L
L
G
E
F
L
R
T
H
K
Y
D
P
A
W
Site 4
Y48
E
F
L
R
T
H
K
Y
D
P
A
W
K
Y
R
Site 5
Y54
K
Y
D
P
A
W
K
Y
R
F
G
D
L
S
V
Site 6
S60
K
Y
R
F
G
D
L
S
V
T
Y
E
P
M
A
Site 7
T62
R
F
G
D
L
S
V
T
Y
E
P
M
A
Y
M
Site 8
Y63
F
G
D
L
S
V
T
Y
E
P
M
A
Y
M
D
Site 9
S101
S
S
N
L
W
V
P
S
V
Y
C
Q
S
Q
A
Site 10
S106
V
P
S
V
Y
C
Q
S
Q
A
C
T
S
H
S
Site 11
S111
C
Q
S
Q
A
C
T
S
H
S
R
F
N
P
S
Site 12
S113
S
Q
A
C
T
S
H
S
R
F
N
P
S
E
S
Site 13
S118
S
H
S
R
F
N
P
S
E
S
S
T
Y
S
T
Site 14
S120
S
R
F
N
P
S
E
S
S
T
Y
S
T
N
G
Site 15
S121
R
F
N
P
S
E
S
S
T
Y
S
T
N
G
Q
Site 16
T122
F
N
P
S
E
S
S
T
Y
S
T
N
G
Q
T
Site 17
Y123
N
P
S
E
S
S
T
Y
S
T
N
G
Q
T
F
Site 18
S124
P
S
E
S
S
T
Y
S
T
N
G
Q
T
F
S
Site 19
T125
S
E
S
S
T
Y
S
T
N
G
Q
T
F
S
L
Site 20
T129
T
Y
S
T
N
G
Q
T
F
S
L
Q
Y
G
S
Site 21
S131
S
T
N
G
Q
T
F
S
L
Q
Y
G
S
G
S
Site 22
Y134
G
Q
T
F
S
L
Q
Y
G
S
G
S
L
T
G
Site 23
S138
S
L
Q
Y
G
S
G
S
L
T
G
F
F
G
Y
Site 24
T140
Q
Y
G
S
G
S
L
T
G
F
F
G
Y
D
T
Site 25
S163
P
N
Q
E
F
G
L
S
E
N
E
P
G
T
N
Site 26
Y173
E
P
G
T
N
F
V
Y
A
Q
F
D
G
I
M
Site 27
Y213
T
S
P
V
F
S
V
Y
L
S
N
Q
Q
G
S
Site 28
S215
P
V
F
S
V
Y
L
S
N
Q
Q
G
S
S
G
Site 29
Y235
G
G
V
D
S
S
L
Y
T
G
Q
I
Y
W
A
Site 30
T236
G
V
D
S
S
L
Y
T
G
Q
I
Y
W
A
P
Site 31
Y240
S
L
Y
T
G
Q
I
Y
W
A
P
V
T
Q
E
Site 32
Y249
A
P
V
T
Q
E
L
Y
W
Q
I
G
I
E
E
Site 33
T283
D
T
G
T
S
L
L
T
V
P
Q
Q
Y
M
S
Site 34
Y303
T
G
A
Q
E
D
E
Y
G
Q
F
L
V
N
C
Site 35
S333
V
E
F
P
L
P
P
S
S
Y
I
L
S
N
N
Site 36
S334
E
F
P
L
P
P
S
S
Y
I
L
S
N
N
G
Site 37
S338
P
P
S
S
Y
I
L
S
N
N
G
Y
C
T
V
Site 38
T344
L
S
N
N
G
Y
C
T
V
G
V
E
P
T
Y
Site 39
Y351
T
V
G
V
E
P
T
Y
L
S
S
Q
N
G
Q
Site 40
S353
G
V
E
P
T
Y
L
S
S
Q
N
G
Q
P
L
Site 41
S354
V
E
P
T
Y
L
S
S
Q
N
G
Q
P
L
W
Site 42
Y371
G
D
V
F
L
R
S
Y
Y
S
V
Y
D
L
G
Site 43
Y372
D
V
F
L
R
S
Y
Y
S
V
Y
D
L
G
N
Site 44
S373
V
F
L
R
S
Y
Y
S
V
Y
D
L
G
N
N
Site 45
Y375
L
R
S
Y
Y
S
V
Y
D
L
G
N
N
R
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation