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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TBP
Full Name:
TATA-box-binding protein
Alias:
GTF2D1; SCA17; TATA binding factor; TATA box binding protein; TATA sequence-binding protein; TATA-box binding protein; TATA-box factor; TFIID; transcription initiation factor TFIID TBP subunit
Type:
Transcription initiation complex; Nuclear receptor co-regulator
Mass (Da):
37698
Number AA:
339
UniProt ID:
P20226
International Prot ID:
IPI00022831
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005672
GO:0005669
Uniprot
OncoNet
Molecular Function:
GO:0016251
GO:0010843
GO:0008134
PhosphoSite+
KinaseNET
Biological Process:
GO:0006368
GO:0008219
GO:0032568
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y10
Q
N
N
S
L
P
P
Y
A
Q
G
L
A
S
P
Site 2
S16
P
Y
A
Q
G
L
A
S
P
Q
G
A
M
T
P
Site 3
T39
M
P
Y
G
T
G
L
T
P
Q
P
I
Q
N
T
Site 4
T46
T
P
Q
P
I
Q
N
T
N
S
L
S
I
L
E
Site 5
S48
Q
P
I
Q
N
T
N
S
L
S
I
L
E
E
Q
Site 6
S50
I
Q
N
T
N
S
L
S
I
L
E
E
Q
Q
R
Site 7
S107
A
A
V
Q
Q
S
T
S
Q
Q
A
T
Q
G
T
Site 8
T111
Q
S
T
S
Q
Q
A
T
Q
G
T
S
G
Q
A
Site 9
S124
Q
A
P
Q
L
F
H
S
Q
T
L
T
T
A
P
Site 10
T126
P
Q
L
F
H
S
Q
T
L
T
T
A
P
L
P
Site 11
T135
T
T
A
P
L
P
G
T
T
P
L
Y
P
S
P
Site 12
T136
T
A
P
L
P
G
T
T
P
L
Y
P
S
P
M
Site 13
Y139
L
P
G
T
T
P
L
Y
P
S
P
M
T
P
M
Site 14
S141
G
T
T
P
L
Y
P
S
P
M
T
P
M
T
P
Site 15
T144
P
L
Y
P
S
P
M
T
P
M
T
P
I
T
P
Site 16
T147
P
S
P
M
T
P
M
T
P
I
T
P
A
T
P
Site 17
T150
M
T
P
M
T
P
I
T
P
A
T
P
A
S
E
Site 18
T153
M
T
P
I
T
P
A
T
P
A
S
E
S
S
G
Site 19
T182
G
C
K
L
D
L
K
T
I
A
L
R
A
R
N
Site 20
T210
R
I
R
E
P
R
T
T
A
L
I
F
S
S
G
Site 21
T222
S
S
G
K
M
V
C
T
G
A
K
S
E
E
Q
Site 22
S226
M
V
C
T
G
A
K
S
E
E
Q
S
R
L
A
Site 23
S230
G
A
K
S
E
E
Q
S
R
L
A
A
R
K
Y
Site 24
Y237
S
R
L
A
A
R
K
Y
A
R
V
V
Q
K
L
Site 25
S261
K
I
Q
N
M
V
G
S
C
D
V
K
F
P
I
Site 26
T276
R
L
E
G
L
V
L
T
H
Q
Q
F
S
S
Y
Site 27
S282
L
T
H
Q
Q
F
S
S
Y
E
P
E
L
F
P
Site 28
Y322
A
K
V
R
A
E
I
Y
E
A
F
E
N
I
Y
Site 29
Y329
Y
E
A
F
E
N
I
Y
P
I
L
K
G
F
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation