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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
POU3F3
Full Name:
POU domain, class 3, transcription factor 3
Alias:
Brain-specific homeobox/POU domain protein 1;Octamer-binding protein 8;Octamer-binding transcription factor 8
Type:
Mass (Da):
50327
Number AA:
500
UniProt ID:
P20264
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S55
G
G
G
M
Q
P
G
S
A
A
V
T
S
G
A
Site 2
S60
P
G
S
A
A
V
T
S
G
A
Y
R
G
D
P
Site 3
S69
A
Y
R
G
D
P
S
S
V
K
M
V
Q
S
D
Site 4
S125
A
S
S
P
W
S
G
S
A
V
G
M
A
G
S
Site 5
S132
S
A
V
G
M
A
G
S
P
Q
Q
P
P
Q
P
Site 6
S219
G
Q
Q
P
P
P
Q
S
L
L
Y
S
Q
P
G
Site 7
Y222
P
P
P
Q
S
L
L
Y
S
Q
P
G
G
F
T
Site 8
S223
P
P
Q
S
L
L
Y
S
Q
P
G
G
F
T
V
Site 9
T229
Y
S
Q
P
G
G
F
T
V
N
G
M
L
S
A
Site 10
T264
P
G
L
V
R
G
D
T
P
E
L
A
E
H
H
Site 11
S307
G
A
G
P
G
L
N
S
H
D
P
H
S
D
E
Site 12
S312
L
N
S
H
D
P
H
S
D
E
D
T
P
T
S
Site 13
T316
D
P
H
S
D
E
D
T
P
T
S
D
D
L
E
Site 14
T318
H
S
D
E
D
T
P
T
S
D
D
L
E
Q
F
Site 15
S319
S
D
E
D
T
P
T
S
D
D
L
E
Q
F
A
Site 16
S369
R
F
E
A
L
Q
L
S
F
K
N
M
C
K
L
Site 17
S389
K
W
L
E
E
A
D
S
S
T
G
S
P
T
S
Site 18
S390
W
L
E
E
A
D
S
S
T
G
S
P
T
S
I
Site 19
T391
L
E
E
A
D
S
S
T
G
S
P
T
S
I
D
Site 20
S393
E
A
D
S
S
T
G
S
P
T
S
I
D
K
I
Site 21
S396
S
S
T
G
S
P
T
S
I
D
K
I
A
A
Q
Site 22
S412
R
K
R
K
K
R
T
S
I
E
V
S
V
K
G
Site 23
S416
K
R
T
S
I
E
V
S
V
K
G
A
L
E
S
Site 24
S423
S
V
K
G
A
L
E
S
H
F
L
K
C
P
K
Site 25
S442
E
I
T
N
L
A
D
S
L
Q
L
E
K
E
V
Site 26
T465
R
Q
K
E
K
R
M
T
P
P
G
I
Q
Q
Q
Site 27
T473
P
P
G
I
Q
Q
Q
T
P
D
D
V
Y
S
Q
Site 28
Y478
Q
Q
T
P
D
D
V
Y
S
Q
V
G
T
V
S
Site 29
S479
Q
T
P
D
D
V
Y
S
Q
V
G
T
V
S
A
Site 30
T483
D
V
Y
S
Q
V
G
T
V
S
A
D
T
P
P
Site 31
S485
Y
S
Q
V
G
T
V
S
A
D
T
P
P
P
H
Site 32
T488
V
G
T
V
S
A
D
T
P
P
P
H
H
G
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation