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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PSMB1
Full Name:
Proteasome subunit beta type-1
Alias:
HC5; Macropain subunit C5; Multicatalytic endopeptidase complex subunit C5; PMSB1; proteasome (prosome, macropain) subunit, beta type, 1; Proteasome gamma chain; Proteasome subunit beta type 1; PSB1; PSC5
Type:
EC 3.4.25.1; Protease; Proteasome complex
Mass (Da):
26489
Number AA:
241
UniProt ID:
P20618
International Prot ID:
IPI00025019
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
GO:0005839
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0004298
PhosphoSite+
KinaseNET
Biological Process:
GO:0031145
GO:0051436
GO:0051437
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y8
M
L
S
S
T
A
M
Y
S
A
P
G
R
D
L
Site 2
S9
L
S
S
T
A
M
Y
S
A
P
G
R
D
L
G
Site 3
S31
G
P
L
Q
L
R
F
S
P
Y
V
F
N
G
G
Site 4
S53
E
D
F
A
I
V
A
S
D
T
R
L
S
E
G
Site 5
S58
V
A
S
D
T
R
L
S
E
G
F
S
I
H
T
Site 6
S62
T
R
L
S
E
G
F
S
I
H
T
R
D
S
P
Site 7
S68
F
S
I
H
T
R
D
S
P
K
C
Y
K
L
T
Site 8
Y72
T
R
D
S
P
K
C
Y
K
L
T
D
K
T
V
Site 9
T75
S
P
K
C
Y
K
L
T
D
K
T
V
I
G
C
Site 10
T78
C
Y
K
L
T
D
K
T
V
I
G
C
S
G
F
Site 11
S83
D
K
T
V
I
G
C
S
G
F
H
G
D
C
L
Site 12
T91
G
F
H
G
D
C
L
T
L
T
K
I
I
E
A
Site 13
T93
H
G
D
C
L
T
L
T
K
I
I
E
A
R
L
Site 14
Y103
I
E
A
R
L
K
M
Y
K
H
S
N
N
K
A
Site 15
Y125
A
M
L
S
T
I
L
Y
S
R
R
F
F
P
Y
Site 16
Y132
Y
S
R
R
F
F
P
Y
Y
V
Y
N
I
I
G
Site 17
Y133
S
R
R
F
F
P
Y
Y
V
Y
N
I
I
G
G
Site 18
Y135
R
F
F
P
Y
Y
V
Y
N
I
I
G
G
L
D
Site 19
Y150
E
E
G
K
G
A
V
Y
S
F
D
P
V
G
S
Site 20
S151
E
G
K
G
A
V
Y
S
F
D
P
V
G
S
Y
Site 21
S157
Y
S
F
D
P
V
G
S
Y
Q
R
D
S
F
K
Site 22
Y158
S
F
D
P
V
G
S
Y
Q
R
D
S
F
K
A
Site 23
S162
V
G
S
Y
Q
R
D
S
F
K
A
G
G
S
A
Site 24
S168
D
S
F
K
A
G
G
S
A
S
A
M
L
Q
P
Site 25
S195
N
V
E
H
V
P
L
S
L
D
R
A
M
R
L
Site 26
S209
L
V
K
D
V
F
I
S
A
A
E
R
D
V
Y
Site 27
Y216
S
A
A
E
R
D
V
Y
T
G
D
A
L
R
I
Site 28
T235
K
E
G
I
R
E
E
T
V
S
L
R
K
D
_
Site 29
S237
G
I
R
E
E
T
V
S
L
R
K
D
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation