PhosphoNET

           
Protein Info 
   
Short Name:  AGXT
Full Name:  Serine--pyruvate aminotransferase
Alias:  AGT; AGT1; AGXT1; Alanine-glyoxylate aminotransferase; EC 2.6.1.44; EC 2.6.1.51; Glycolicaciduria; L-alanine: glyoxylate aminotransferase 1; Oxalosis I; PH1; Primary hyperoxaluria type 1; Serine:pyruvate aminotransferase; Serine-pyruvate aminotransferase; SPAT; SPT; SPYA; TLH6
Type:  Transferase; Amino Acid Metabolism - glycine, serine and threonine; EC 2.6.1.44; Mitochondrial; Amino Acid Metabolism - alanine, aspartate and glutamate; EC 2.6.1.51
Mass (Da):  43010
Number AA:  392
UniProt ID:  P21549
International Prot ID:  IPI00009367
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005759  GO:0005777   Uniprot OncoNet
Molecular Function:  GO:0008453  GO:0042803  GO:0030170 PhosphoSite+ KinaseNET
Biological Process:  GO:0046487  GO:0006625   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S48GGLQMIGSMSKDMYQ
Site 2Y54GSMSKDMYQIMDEIK
Site 3Y66EIKEGIQYVFQTRNP
Site 4T127GARVHPMTKDPGGHY
Site 5T191SVASLGGTPLYMDRQ
Site 6Y194SLGGTPLYMDRQGID
Site 7Y204RQGIDILYSGSQKAL
Site 8S205QGIDILYSGSQKALN
Site 9S207IDILYSGSQKALNAP
Site 10S218LNAPPGTSLISFSDK
Site 11S221PPGTSLISFSDKAKK
Site 12Y231DKAKKKMYSRKTKPF
Site 13T235KKMYSRKTKPFSFYL
Site 14S239SRKTKPFSFYLDIKW
Site 15Y241KTKPFSFYLDIKWLA
Site 16Y260CDDQPRMYHHTIPVI
Site 17T263QPRMYHHTIPVISLY
Site 18S268HHTIPVISLYSLRES
Site 19S287AEQGLENSWRQHREA
Site 20Y297QHREAAAYLHGRLQA
Site 21Y338DWRDIVSYVIDHFDI
Site 22T377RENVDRVTEALRAAL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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