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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SYT1
Full Name:
Synaptotagmin-1
Alias:
P65; SVP65; SYT
Type:
Vesicle protein; Calcium-binding protein
Mass (Da):
47573
Number AA:
422
UniProt ID:
P21579
International Prot ID:
IPI00009439
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0060201
GO:0030666
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0050750
GO:0005545
PhosphoSite+
KinaseNET
Biological Process:
GO:0005513
GO:0007269
GO:0051260
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S24
T
V
A
T
V
L
P
S
N
A
T
E
P
A
S
Site 2
T27
T
V
L
P
S
N
A
T
E
P
A
S
P
G
E
Site 3
S31
S
N
A
T
E
P
A
S
P
G
E
G
K
E
D
Site 4
S41
E
G
K
E
D
A
F
S
K
L
K
E
K
F
M
Site 5
T113
D
V
K
D
L
G
K
T
M
K
D
Q
A
L
K
Site 6
T126
L
K
D
D
D
A
E
T
G
L
T
D
G
E
E
Site 7
T129
D
D
A
E
T
G
L
T
D
G
E
E
K
E
E
Site 8
S149
K
L
G
K
L
Q
Y
S
L
D
Y
D
F
Q
N
Site 9
Y152
K
L
Q
Y
S
L
D
Y
D
F
Q
N
N
Q
L
Site 10
T202
E
T
K
V
H
R
K
T
L
N
P
V
F
N
E
Site 11
T212
P
V
F
N
E
Q
F
T
F
K
V
P
Y
S
E
Site 12
Y217
Q
F
T
F
K
V
P
Y
S
E
L
G
G
K
T
Site 13
S218
F
T
F
K
V
P
Y
S
E
L
G
G
K
T
L
Site 14
Y230
K
T
L
V
M
A
V
Y
D
F
D
R
F
S
K
Site 15
T250
E
F
K
V
P
M
N
T
V
D
F
G
H
V
T
Site 16
S265
E
E
W
R
D
L
Q
S
A
E
K
E
E
Q
E
Site 17
S309
K
M
D
V
G
G
L
S
D
P
Y
V
K
I
H
Site 18
Y312
V
G
G
L
S
D
P
Y
V
K
I
H
L
M
Q
Site 19
T329
K
R
L
K
K
K
K
T
T
I
K
K
N
T
L
Site 20
T335
K
T
T
I
K
K
N
T
L
N
P
Y
Y
N
E
Site 21
Y339
K
K
N
T
L
N
P
Y
Y
N
E
S
F
S
F
Site 22
Y340
K
N
T
L
N
P
Y
Y
N
E
S
F
S
F
E
Site 23
S343
L
N
P
Y
Y
N
E
S
F
S
F
E
V
P
F
Site 24
S345
P
Y
Y
N
E
S
F
S
F
E
V
P
F
E
Q
Site 25
Y365
V
V
V
T
V
L
D
Y
D
K
I
G
K
N
D
Site 26
Y381
I
G
K
V
F
V
G
Y
N
S
T
G
A
E
L
Site 27
S383
K
V
F
V
G
Y
N
S
T
G
A
E
L
R
H
Site 28
S392
G
A
E
L
R
H
W
S
D
M
L
A
N
P
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation