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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IBSP
Full Name:
Bone sialoprotein 2
Alias:
BNSP; Bone sialoprotein; Bone sialoprotein II; BSP; BSP II; BSP-II; Cell- binding sialoprotein; Integrin-binding sialoprotein; SIAL; SP-II
Type:
Secreted protein; Adhesion
Mass (Da):
35018
Number AA:
317
UniProt ID:
P21815
International Prot ID:
IPI00294662
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0031214
GO:0007155
GO:0001503
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T3
_
_
_
_
_
M
K
T
A
L
I
L
L
S
I
Site 2
S31
R
R
V
K
I
E
D
S
E
E
N
G
V
F
K
Site 3
Y39
E
E
N
G
V
F
K
Y
R
P
R
Y
Y
L
Y
Site 4
Y43
V
F
K
Y
R
P
R
Y
Y
L
Y
K
H
A
Y
Site 5
Y44
F
K
Y
R
P
R
Y
Y
L
Y
K
H
A
Y
F
Site 6
Y46
Y
R
P
R
Y
Y
L
Y
K
H
A
Y
F
Y
P
Site 7
Y50
Y
Y
L
Y
K
H
A
Y
F
Y
P
H
L
K
R
Site 8
Y52
L
Y
K
H
A
Y
F
Y
P
H
L
K
R
F
P
Site 9
S63
K
R
F
P
V
Q
G
S
S
D
S
S
E
E
N
Site 10
S64
R
F
P
V
Q
G
S
S
D
S
S
E
E
N
G
Site 11
S66
P
V
Q
G
S
S
D
S
S
E
E
N
G
D
D
Site 12
S67
V
Q
G
S
S
D
S
S
E
E
N
G
D
D
S
Site 13
S74
S
E
E
N
G
D
D
S
S
E
E
E
E
E
E
Site 14
S75
E
E
N
G
D
D
S
S
E
E
E
E
E
E
E
Site 15
T84
E
E
E
E
E
E
E
T
S
N
E
G
E
N
N
Site 16
S85
E
E
E
E
E
E
T
S
N
E
G
E
N
N
E
Site 17
S94
E
G
E
N
N
E
E
S
N
E
D
E
D
S
E
Site 18
S100
E
S
N
E
D
E
D
S
E
A
E
N
T
T
L
Site 19
T105
E
D
S
E
A
E
N
T
T
L
S
A
T
T
L
Site 20
T106
D
S
E
A
E
N
T
T
L
S
A
T
T
L
G
Site 21
S108
E
A
E
N
T
T
L
S
A
T
T
L
G
Y
G
Site 22
T119
L
G
Y
G
E
D
A
T
P
G
T
G
Y
T
G
Site 23
T140
P
K
K
A
G
D
I
T
N
K
A
T
K
E
K
Site 24
S149
K
A
T
K
E
K
E
S
D
E
E
E
E
E
E
Site 25
S165
E
G
N
E
N
E
E
S
E
A
E
V
D
E
N
Site 26
T184
N
G
T
S
T
N
S
T
E
A
E
N
G
N
G
Site 27
S205
G
E
E
G
E
E
E
S
V
T
G
A
N
A
E
Site 28
T207
E
G
E
E
E
S
V
T
G
A
N
A
E
G
T
Site 29
T224
T
G
R
Q
G
K
G
T
S
K
T
T
T
S
P
Site 30
S225
G
R
Q
G
K
G
T
S
K
T
T
T
S
P
N
Site 31
T227
Q
G
K
G
T
S
K
T
T
T
S
P
N
G
G
Site 32
T228
G
K
G
T
S
K
T
T
T
S
P
N
G
G
F
Site 33
T229
K
G
T
S
K
T
T
T
S
P
N
G
G
F
E
Site 34
S230
G
T
S
K
T
T
T
S
P
N
G
G
F
E
P
Site 35
T238
P
N
G
G
F
E
P
T
T
P
P
Q
V
Y
R
Site 36
T239
N
G
G
F
E
P
T
T
P
P
Q
V
Y
R
T
Site 37
Y244
P
T
T
P
P
Q
V
Y
R
T
T
S
P
P
F
Site 38
T246
T
P
P
Q
V
Y
R
T
T
S
P
P
F
G
K
Site 39
T247
P
P
Q
V
Y
R
T
T
S
P
P
F
G
K
T
Site 40
S248
P
Q
V
Y
R
T
T
S
P
P
F
G
K
T
T
Site 41
T256
P
P
F
G
K
T
T
T
V
E
Y
E
G
E
Y
Site 42
Y263
T
V
E
Y
E
G
E
Y
E
Y
T
G
A
N
E
Site 43
Y265
E
Y
E
G
E
Y
E
Y
T
G
A
N
E
Y
D
Site 44
T266
Y
E
G
E
Y
E
Y
T
G
A
N
E
Y
D
N
Site 45
Y271
E
Y
T
G
A
N
E
Y
D
N
G
Y
E
I
Y
Site 46
Y275
A
N
E
Y
D
N
G
Y
E
I
Y
E
S
E
N
Site 47
Y278
Y
D
N
G
Y
E
I
Y
E
S
E
N
G
E
P
Site 48
S280
N
G
Y
E
I
Y
E
S
E
N
G
E
P
R
G
Site 49
Y290
G
E
P
R
G
D
N
Y
R
A
Y
E
D
E
Y
Site 50
Y293
R
G
D
N
Y
R
A
Y
E
D
E
Y
S
Y
F
Site 51
Y297
Y
R
A
Y
E
D
E
Y
S
Y
F
K
G
Q
G
Site 52
Y299
A
Y
E
D
E
Y
S
Y
F
K
G
Q
G
Y
D
Site 53
Y305
S
Y
F
K
G
Q
G
Y
D
G
Y
D
G
Q
N
Site 54
Y308
K
G
Q
G
Y
D
G
Y
D
G
Q
N
Y
Y
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation