PhosphoNET

           
Protein Info 
   
Short Name:  SDHB
Full Name:  Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Alias:  Ip
Type: 
Mass (Da):  31612
Number AA:  280
UniProt ID:  P21912
International Prot ID:  IPI00294911
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005739  GO:0005743  GO:0016020 Uniprot OncoNet
Molecular Function:  GO:0003824  GO:0005488  GO:0005506 PhosphoSite+ KinaseNET
Biological Process:  GO:0006084  GO:0006091  GO:0006099 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T17RRRLPATTLGGACLQ
Site 2S26GGACLQASRGAQTAA
Site 3Y61DKPHMQTYEVDLNKC
Site 4S85KIKNEVDSTLTFRRS
Site 5T86IKNEVDSTLTFRRSC
Site 6T88NEVDSTLTFRRSCRE
Site 7S92STLTFRRSCREGICG
Site 8T114GGNTLACTRRIDTNL
Site 9T119ACTRRIDTNLNKVSK
Site 10Y128LNKVSKIYPLPHMYV
Site 11S144KDLVPDLSNFYAQYK
Site 12Y150LSNFYAQYKSIEPYL
Site 13Y156QYKSIEPYLKKKDES
Site 14S163YLKKKDESQEGKQQY
Site 15Y170SQEGKQQYLQSIEER
Site 16S173GKQQYLQSIEEREKL
Site 17Y206YWWNGDKYLGPAVLM
Site 18Y216PAVLMQAYRWMIDSR
Site 19S222AYRWMIDSRDDFTEE
Site 20T227IDSRDDFTEERLAKL
Site 21S239AKLQDPFSLYRCHTI
Site 22Y241LQDPFSLYRCHTIMN
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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