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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BMP6
Full Name:
Bone morphogenetic protein 6
Alias:
VG-1-related protein
Type:
Mass (Da):
57226
Number AA:
513
UniProt ID:
P22004
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S49
Q
L
L
G
D
G
G
S
P
G
R
T
E
Q
P
Site 2
T53
D
G
G
S
P
G
R
T
E
Q
P
P
P
S
P
Site 3
S59
R
T
E
Q
P
P
P
S
P
Q
S
S
S
G
F
Site 4
S62
Q
P
P
P
S
P
Q
S
S
S
G
F
L
Y
R
Site 5
S63
P
P
P
S
P
Q
S
S
S
G
F
L
Y
R
R
Site 6
S64
P
P
S
P
Q
S
S
S
G
F
L
Y
R
R
L
Site 7
Y68
Q
S
S
S
G
F
L
Y
R
R
L
K
T
Q
E
Site 8
T73
F
L
Y
R
R
L
K
T
Q
E
K
R
E
M
Q
Site 9
S85
E
M
Q
K
E
I
L
S
V
L
G
L
P
H
R
Site 10
S131
P
P
P
G
R
L
K
S
A
P
L
F
M
L
D
Site 11
S144
L
D
L
Y
N
A
L
S
A
D
N
D
E
D
G
Site 12
S153
D
N
D
E
D
G
A
S
E
G
E
R
Q
Q
S
Site 13
S160
S
E
G
E
R
Q
Q
S
W
P
H
E
A
A
S
Site 14
S168
W
P
H
E
A
A
S
S
S
Q
R
R
Q
P
P
Site 15
S169
P
H
E
A
A
S
S
S
Q
R
R
Q
P
P
P
Site 16
S186
A
H
P
L
N
R
K
S
L
L
A
P
G
S
G
Site 17
S192
K
S
L
L
A
P
G
S
G
S
G
G
A
S
P
Site 18
S198
G
S
G
S
G
G
A
S
P
L
T
S
A
Q
D
Site 19
T201
S
G
G
A
S
P
L
T
S
A
Q
D
S
A
F
Site 20
S206
P
L
T
S
A
Q
D
S
A
F
L
N
D
A
D
Site 21
Y224
S
F
V
N
L
V
E
Y
D
K
E
F
S
P
R
Site 22
S229
V
E
Y
D
K
E
F
S
P
R
Q
R
H
H
K
Site 23
S243
K
E
F
K
F
N
L
S
Q
I
P
E
G
E
V
Site 24
Y259
T
A
A
E
F
R
I
Y
K
D
C
V
M
G
S
Site 25
Y277
Q
T
F
L
I
S
I
Y
Q
V
L
Q
E
H
Q
Site 26
S288
Q
E
H
Q
H
R
D
S
D
L
F
L
L
D
T
Site 27
S301
D
T
R
V
V
W
A
S
E
E
G
W
L
E
F
Site 28
T320
T
S
N
L
W
V
V
T
P
Q
H
N
M
G
L
Site 29
Y353
L
V
G
R
D
G
P
Y
D
K
Q
P
F
M
V
Site 30
T373
S
E
V
H
V
R
T
T
R
S
A
S
S
R
R
Site 31
S377
V
R
T
T
R
S
A
S
S
R
R
R
Q
Q
S
Site 32
S378
R
T
T
R
S
A
S
S
R
R
R
Q
Q
S
R
Site 33
S384
S
S
R
R
R
Q
Q
S
R
N
R
S
T
Q
S
Site 34
S388
R
Q
Q
S
R
N
R
S
T
Q
S
Q
D
V
A
Site 35
T389
Q
Q
S
R
N
R
S
T
Q
S
Q
D
V
A
R
Site 36
S391
S
R
N
R
S
T
Q
S
Q
D
V
A
R
V
S
Site 37
S398
S
Q
D
V
A
R
V
S
S
A
S
D
Y
N
S
Site 38
S399
Q
D
V
A
R
V
S
S
A
S
D
Y
N
S
S
Site 39
S401
V
A
R
V
S
S
A
S
D
Y
N
S
S
E
L
Site 40
Y403
R
V
S
S
A
S
D
Y
N
S
S
E
L
K
T
Site 41
S405
S
S
A
S
D
Y
N
S
S
E
L
K
T
A
C
Site 42
S406
S
A
S
D
Y
N
S
S
E
L
K
T
A
C
R
Site 43
T410
Y
N
S
S
E
L
K
T
A
C
R
K
H
E
L
Site 44
Y418
A
C
R
K
H
E
L
Y
V
S
F
Q
D
L
G
Site 45
S420
R
K
H
E
L
Y
V
S
F
Q
D
L
G
W
Q
Site 46
Y440
P
K
G
Y
A
A
N
Y
C
D
G
E
C
S
F
Site 47
S487
P
T
K
L
N
A
I
S
V
L
Y
F
D
D
N
Site 48
Y502
S
N
V
I
L
K
K
Y
R
N
M
V
V
R
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation