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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MUT
Full Name:
Methylmalonyl-CoA mutase, mitochondrial
Alias:
Methylmalonyl-CoA isomerase
Type:
Mass (Da):
83102
Number AA:
750
UniProt ID:
P22033
International Prot ID:
IPI00024934
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005739
GO:0005759
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0003824
GO:0004494
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0008152
GO:0009791
GO:0032502
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
K
N
Q
L
F
L
L
S
P
H
Y
L
R
Q
V
Site 2
Y15
L
F
L
L
S
P
H
Y
L
R
Q
V
K
E
S
Site 3
S22
Y
L
R
Q
V
K
E
S
S
G
S
R
L
I
Q
Site 4
S23
L
R
Q
V
K
E
S
S
G
S
R
L
I
Q
Q
Site 5
T63
P
E
D
L
I
W
H
T
P
E
G
I
S
I
K
Site 6
Y73
G
I
S
I
K
P
L
Y
S
K
R
D
T
M
D
Site 7
S74
I
S
I
K
P
L
Y
S
K
R
D
T
M
D
L
Site 8
T78
P
L
Y
S
K
R
D
T
M
D
L
P
E
E
L
Site 9
T92
L
P
G
V
K
P
F
T
R
G
P
Y
P
T
M
Site 10
Y96
K
P
F
T
R
G
P
Y
P
T
M
Y
T
F
R
Site 11
Y100
R
G
P
Y
P
T
M
Y
T
F
R
P
W
T
I
Site 12
Y110
R
P
W
T
I
R
Q
Y
A
G
F
S
T
V
E
Site 13
S114
I
R
Q
Y
A
G
F
S
T
V
E
E
S
N
K
Site 14
T115
R
Q
Y
A
G
F
S
T
V
E
E
S
N
K
F
Site 15
Y123
V
E
E
S
N
K
F
Y
K
D
N
I
K
A
G
Site 16
T142
S
V
A
F
D
L
A
T
H
R
G
Y
D
S
D
Site 17
Y146
D
L
A
T
H
R
G
Y
D
S
D
N
P
R
V
Site 18
S148
A
T
H
R
G
Y
D
S
D
N
P
R
V
R
G
Site 19
T216
P
K
E
K
L
T
G
T
I
Q
N
D
I
L
K
Site 20
T230
K
E
F
M
V
R
N
T
Y
I
F
P
P
E
P
Site 21
Y231
E
F
M
V
R
N
T
Y
I
F
P
P
E
P
S
Site 22
S238
Y
I
F
P
P
E
P
S
M
K
I
I
A
D
I
Site 23
Y248
I
I
A
D
I
F
E
Y
T
A
K
H
M
P
K
Site 24
T249
I
A
D
I
F
E
Y
T
A
K
H
M
P
K
F
Site 25
S262
K
F
N
S
I
S
I
S
G
Y
H
M
Q
E
A
Site 26
Y264
N
S
I
S
I
S
G
Y
H
M
Q
E
A
G
A
Site 27
Y287
T
L
A
D
G
L
E
Y
S
R
T
G
L
Q
A
Site 28
S288
L
A
D
G
L
E
Y
S
R
T
G
L
Q
A
G
Site 29
T290
D
G
L
E
Y
S
R
T
G
L
Q
A
G
L
T
Site 30
T297
T
G
L
Q
A
G
L
T
I
D
E
F
A
P
R
Site 31
S344
F
Q
P
K
N
S
K
S
L
L
L
R
A
H
C
Site 32
T353
L
L
R
A
H
C
Q
T
S
G
W
S
L
T
E
Site 33
Y364
S
L
T
E
Q
D
P
Y
N
N
I
V
R
T
A
Site 34
S384
A
V
F
G
G
T
Q
S
L
H
T
N
S
F
D
Site 35
S389
T
Q
S
L
H
T
N
S
F
D
E
A
L
G
L
Site 36
S401
L
G
L
P
T
V
K
S
A
R
I
A
R
N
T
Site 37
T408
S
A
R
I
A
R
N
T
Q
I
I
I
Q
E
E
Site 38
S481
R
R
Q
A
R
I
D
S
G
S
E
V
I
V
G
Site 39
T508
E
V
L
A
I
D
N
T
S
V
R
N
R
Q
I
Site 40
S509
V
L
A
I
D
N
T
S
V
R
N
R
Q
I
E
Site 41
S523
E
K
L
K
K
I
K
S
S
R
D
Q
A
L
A
Site 42
T561
D
A
S
R
A
R
C
T
V
G
E
I
T
D
A
Site 43
S584
K
A
N
D
R
M
V
S
G
A
Y
R
Q
E
F
Site 44
S594
Y
R
Q
E
F
G
E
S
K
E
I
T
S
A
I
Site 45
T598
F
G
E
S
K
E
I
T
S
A
I
K
R
V
H
Site 46
S599
G
E
S
K
E
I
T
S
A
I
K
R
V
H
K
Site 47
T653
D
I
G
P
L
F
Q
T
P
R
E
V
A
Q
Q
Site 48
S691
E
L
I
K
E
L
N
S
L
G
R
P
D
I
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation