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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FBL
Full Name:
rRNA 2'-O-methyltransferase fibrillarin
Alias:
34 kDa nucleolar scleroderma antigen; 34-kD nucleolar scleroderma antigen; FBRL; FIB; FIB1; fibrillarin; FLRN; RNA, U3 small nucleolar interacting protein 1; RNU3IP1
Type:
Methyltransferase; EC 2.1.1.-; RNA processing; RNA binding protein
Mass (Da):
33784
Number AA:
321
UniProt ID:
P22087
International Prot ID:
IPI00025039
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0031428
GO:0031428
GO:0015030
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0008168
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006364
GO:0008033
GO:0006396
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
K
P
G
F
S
P
R
G
G
G
F
G
Site 2
S66
R
G
G
G
G
F
H
S
G
G
N
R
G
R
G
Site 3
S116
K
N
L
V
P
G
E
S
V
Y
G
E
K
R
V
Site 4
Y118
L
V
P
G
E
S
V
Y
G
E
K
R
V
S
I
Site 5
S124
V
Y
G
E
K
R
V
S
I
S
E
G
D
D
K
Site 6
S126
G
E
K
R
V
S
I
S
E
G
D
D
K
I
E
Site 7
Y134
E
G
D
D
K
I
E
Y
R
A
W
N
P
F
R
Site 8
S178
G
T
T
V
S
H
V
S
D
I
V
G
P
D
G
Site 9
S193
L
V
Y
A
V
E
F
S
H
R
S
G
R
D
L
Site 10
S196
A
V
E
F
S
H
R
S
G
R
D
L
I
N
L
Site 11
T208
I
N
L
A
K
K
R
T
N
I
I
P
V
I
E
Site 12
Y223
D
A
R
H
P
H
K
Y
R
M
L
I
A
M
V
Site 13
T298
M
K
P
Q
E
Q
L
T
L
E
P
Y
E
R
D
Site 14
Y302
E
Q
L
T
L
E
P
Y
E
R
D
H
A
V
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation