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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SCP2
Full Name:
Non-specific lipid-transfer protein
Alias:
NLTP; Nonspecific lipid-transfer protein, mitochondrial; NSL-TP; SCP-2; SCPX; SCP-X; Sterol carrier protein 2
Type:
Transferase; Lipid binding protein; Mitochondrial; Lipid Metabolism - primary bile acid biosynthesis; EC 2.3.1.176
Mass (Da):
58994
Number AA:
547
UniProt ID:
P22307
International Prot ID:
IPI00026105
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005739
GO:0005777
Uniprot
OncoNet
Molecular Function:
GO:0016491
GO:0033814
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006869
GO:0006694
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T10
S
S
P
W
E
P
A
T
L
R
R
V
F
V
V
Site 2
Y35
G
A
E
N
S
R
D
Y
P
D
L
A
E
E
A
Site 3
Y77
T
C
G
Q
R
A
I
Y
H
S
L
G
M
T
G
Site 4
S79
G
Q
R
A
I
Y
H
S
L
G
M
T
G
I
P
Site 5
S125
A
L
G
F
E
K
M
S
K
G
S
L
G
I
K
Site 6
S128
F
E
K
M
S
K
G
S
L
G
I
K
F
S
D
Site 7
S134
G
S
L
G
I
K
F
S
D
R
T
I
P
T
D
Site 8
T137
G
I
K
F
S
D
R
T
I
P
T
D
K
H
V
Site 9
Y174
G
K
E
H
M
E
K
Y
G
T
K
I
E
H
F
Site 10
S192
G
W
K
N
H
K
H
S
V
N
N
P
Y
S
Q
Site 11
Y197
K
H
S
V
N
N
P
Y
S
Q
F
Q
D
E
Y
Site 12
S198
H
S
V
N
N
P
Y
S
Q
F
Q
D
E
Y
S
Site 13
Y204
Y
S
Q
F
Q
D
E
Y
S
L
D
E
V
M
A
Site 14
S205
S
Q
F
Q
D
E
Y
S
L
D
E
V
M
A
S
Site 15
Y245
S
E
A
F
V
Q
K
Y
G
L
Q
S
K
A
V
Site 16
S265
E
M
M
T
D
L
P
S
S
F
E
E
K
S
I
Site 17
S266
M
M
T
D
L
P
S
S
F
E
E
K
S
I
I
Site 18
S271
P
S
S
F
E
E
K
S
I
I
K
M
V
G
F
Site 19
S281
K
M
V
G
F
D
M
S
K
E
A
A
R
K
C
Site 20
Y289
K
E
A
A
R
K
C
Y
E
K
S
G
L
T
P
Site 21
T295
C
Y
E
K
S
G
L
T
P
N
D
I
D
V
I
Site 22
T337
L
V
D
R
G
D
N
T
Y
G
G
K
W
V
I
Site 23
Y338
V
D
R
G
D
N
T
Y
G
G
K
W
V
I
N
Site 24
S347
G
K
W
V
I
N
P
S
G
G
L
I
S
K
G
Site 25
S352
N
P
S
G
G
L
I
S
K
G
H
P
L
G
A
Site 26
Y403
G
A
V
V
V
T
L
Y
K
M
G
F
P
E
A
Site 27
S412
M
G
F
P
E
A
A
S
S
F
R
T
H
Q
I
Site 28
S413
G
F
P
E
A
A
S
S
F
R
T
H
Q
I
E
Site 29
T424
H
Q
I
E
A
V
P
T
S
S
A
S
D
G
F
Site 30
S425
Q
I
E
A
V
P
T
S
S
A
S
D
G
F
K
Site 31
S484
D
V
K
N
G
K
G
S
V
L
P
N
S
D
K
Site 32
S489
K
G
S
V
L
P
N
S
D
K
K
A
D
C
T
Site 33
T496
S
D
K
K
A
D
C
T
I
T
M
A
D
S
D
Site 34
T498
K
K
A
D
C
T
I
T
M
A
D
S
D
F
L
Site 35
S516
T
G
K
M
N
P
Q
S
A
F
F
Q
G
K
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation