KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
UGT1A1
Full Name:
UDP-glucuronosyltransferase 1-1
Alias:
Bilirubin-specific UDPGT isozyme 1;UDP-glucuronosyltransferase 1-A;UDP-glucuronosyltransferase 1A1
Type:
Mass (Da):
59591
Number AA:
533
UniProt ID:
P22309
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y74
Y
I
R
D
G
A
F
Y
T
L
K
T
Y
P
V
Site 2
T75
I
R
D
G
A
F
Y
T
L
K
T
Y
P
V
P
Site 3
T78
G
A
F
Y
T
L
K
T
Y
P
V
P
F
Q
R
Site 4
Y79
A
F
Y
T
L
K
T
Y
P
V
P
F
Q
R
E
Site 5
S91
Q
R
E
D
V
K
E
S
F
V
S
L
G
H
N
Site 6
S94
D
V
K
E
S
F
V
S
L
G
H
N
V
F
E
Site 7
S104
H
N
V
F
E
N
D
S
F
L
Q
R
V
I
K
Site 8
Y113
L
Q
R
V
I
K
T
Y
K
K
I
K
K
D
S
Site 9
S120
Y
K
K
I
K
K
D
S
A
M
L
L
S
G
C
Site 10
S139
H
N
K
E
L
M
A
S
L
A
E
S
S
F
D
Site 11
T184
C
S
L
E
F
E
A
T
Q
C
P
N
P
F
S
Site 12
S191
T
Q
C
P
N
P
F
S
Y
V
P
R
P
L
S
Site 13
Y192
Q
C
P
N
P
F
S
Y
V
P
R
P
L
S
S
Site 14
S198
S
Y
V
P
R
P
L
S
S
H
S
D
H
M
T
Site 15
S199
Y
V
P
R
P
L
S
S
H
S
D
H
M
T
F
Site 16
S201
P
R
P
L
S
S
H
S
D
H
M
T
F
L
Q
Site 17
T205
S
S
H
S
D
H
M
T
F
L
Q
R
V
K
N
Site 18
T243
E
F
L
Q
R
E
V
T
V
Q
D
L
L
S
S
Site 19
S252
Q
D
L
L
S
S
A
S
V
W
L
F
R
S
D
Site 20
S258
A
S
V
W
L
F
R
S
D
F
V
K
D
Y
P
Site 21
Y264
R
S
D
F
V
K
D
Y
P
R
P
I
M
P
N
Site 22
Y293
L
S
Q
E
F
E
A
Y
I
N
A
S
G
E
H
Site 23
S312
F
S
L
G
S
M
V
S
E
I
P
E
K
K
A
Site 24
T332
A
L
G
K
I
P
Q
T
V
L
W
R
Y
T
G
Site 25
Y337
P
Q
T
V
L
W
R
Y
T
G
T
R
P
S
N
Site 26
T338
Q
T
V
L
W
R
Y
T
G
T
R
P
S
N
L
Site 27
S343
R
Y
T
G
T
R
P
S
N
L
A
N
N
T
I
Site 28
Y379
H
A
G
S
H
G
V
Y
E
S
I
C
N
G
V
Site 29
T406
D
N
A
K
R
M
E
T
K
G
A
G
V
T
L
Site 30
S435
K
A
V
I
N
D
K
S
Y
K
E
N
I
M
R
Site 31
Y436
A
V
I
N
D
K
S
Y
K
E
N
I
M
R
L
Site 32
S444
K
E
N
I
M
R
L
S
S
L
H
K
D
R
P
Site 33
S445
E
N
I
M
R
L
S
S
L
H
K
D
R
P
V
Site 34
Y484
A
A
H
D
L
T
W
Y
Q
Y
H
S
L
D
V
Site 35
Y486
H
D
L
T
W
Y
Q
Y
H
S
L
D
V
I
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation