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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
UGT1A4
Full Name:
UDP-glucuronosyltransferase 1-4
Alias:
Bilirubin-specific UDPGT isozyme 2;UDP-glucuronosyltransferase 1-D;UDP-glucuronosyltransferase 1A4
Type:
Mass (Da):
60025
Number AA:
534
UniProt ID:
P22310
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T14
V
P
L
P
R
L
A
T
G
L
L
L
L
L
S
Site 2
S21
T
G
L
L
L
L
L
S
V
Q
P
W
A
E
S
Site 3
S39
L
V
V
P
T
D
G
S
P
W
L
S
M
R
E
Site 4
S43
T
D
G
S
P
W
L
S
M
R
E
A
L
R
E
Site 5
T78
E
E
K
F
F
T
L
T
A
Y
A
V
P
W
T
Site 6
Y80
K
F
F
T
L
T
A
Y
A
V
P
W
T
Q
K
Site 7
T93
Q
K
E
F
D
R
V
T
L
G
Y
T
Q
G
F
Site 8
Y96
F
D
R
V
T
L
G
Y
T
Q
G
F
F
E
T
Site 9
Y110
T
E
H
L
L
K
R
Y
S
R
S
M
A
I
M
Site 10
S111
E
H
L
L
K
R
Y
S
R
S
M
A
I
M
N
Site 11
T185
C
D
L
D
F
K
G
T
Q
C
P
N
P
S
S
Site 12
S192
T
Q
C
P
N
P
S
S
Y
I
P
K
L
L
T
Site 13
T199
S
Y
I
P
K
L
L
T
T
N
S
D
H
M
T
Site 14
S202
P
K
L
L
T
T
N
S
D
H
M
T
F
L
Q
Site 15
T206
T
T
N
S
D
H
M
T
F
L
Q
R
V
K
N
Site 16
Y265
R
G
D
F
V
M
D
Y
P
R
P
I
M
P
N
Site 17
S288
C
A
N
G
K
P
L
S
Q
E
F
E
A
Y
I
Site 18
Y294
L
S
Q
E
F
E
A
Y
I
N
A
S
G
E
H
Site 19
S313
F
S
L
G
S
M
V
S
E
I
P
E
K
K
A
Site 20
T333
A
L
G
K
I
P
Q
T
V
L
W
R
Y
T
G
Site 21
Y338
P
Q
T
V
L
W
R
Y
T
G
T
R
P
S
N
Site 22
T339
Q
T
V
L
W
R
Y
T
G
T
R
P
S
N
L
Site 23
S344
R
Y
T
G
T
R
P
S
N
L
A
N
N
T
I
Site 24
Y380
H
A
G
S
H
G
V
Y
E
S
I
C
N
G
V
Site 25
T407
D
N
A
K
R
M
E
T
K
G
A
G
V
T
L
Site 26
S436
K
A
V
I
N
D
K
S
Y
K
E
N
I
M
R
Site 27
Y437
A
V
I
N
D
K
S
Y
K
E
N
I
M
R
L
Site 28
S445
K
E
N
I
M
R
L
S
S
L
H
K
D
R
P
Site 29
S446
E
N
I
M
R
L
S
S
L
H
K
D
R
P
V
Site 30
Y485
A
A
H
D
L
T
W
Y
Q
Y
H
S
L
D
V
Site 31
Y487
H
D
L
T
W
Y
Q
Y
H
S
L
D
V
I
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation