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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Kv1.5
Full Name:
Potassium voltage-gated channel subfamily A member 5
Alias:
HPCN1;Voltage-gated potassium channel HK2;Voltage-gated potassium channel subunit Kv1.5
Type:
Channel protein, potassium
Mass (Da):
67228
Number AA:
613
UniProt ID:
P22460
International Prot ID:
IPI00304594
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0008076
Uniprot
OncoNet
Molecular Function:
GO:0005251
GO:0030955
PhosphoSite+
KinaseNET
Biological Process:
GO:0006813
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T15
L
E
N
G
G
A
M
T
V
R
G
G
D
E
A
Site 2
T39
G
E
L
Q
C
P
P
T
A
G
L
S
D
G
P
Site 3
S43
C
P
P
T
A
G
L
S
D
G
P
K
E
P
A
Site 4
S62
G
A
Q
R
D
A
D
S
G
V
R
P
L
P
P
Site 5
T106
E
G
D
P
G
L
G
T
V
E
D
Q
A
L
G
Site 6
S116
D
Q
A
L
G
T
A
S
L
H
H
Q
R
V
H
Site 7
S127
Q
R
V
H
I
N
I
S
G
L
R
F
E
T
Q
Site 8
T137
R
F
E
T
Q
L
G
T
L
A
Q
F
P
N
T
Site 9
T144
T
L
A
Q
F
P
N
T
L
L
G
D
P
A
K
Site 10
Y155
D
P
A
K
R
L
R
Y
F
D
P
L
R
N
E
Site 11
Y163
F
D
P
L
R
N
E
Y
F
F
D
R
N
R
P
Site 12
S171
F
F
D
R
N
R
P
S
F
D
G
I
L
Y
Y
Site 13
Y177
P
S
F
D
G
I
L
Y
Y
Y
Q
S
G
G
R
Site 14
Y178
S
F
D
G
I
L
Y
Y
Y
Q
S
G
G
R
L
Site 15
Y179
F
D
G
I
L
Y
Y
Y
Q
S
G
G
R
L
R
Site 16
S181
G
I
L
Y
Y
Y
Q
S
G
G
R
L
R
R
P
Site 17
S192
L
R
R
P
V
N
V
S
L
D
V
F
A
D
E
Site 18
Y203
F
A
D
E
I
R
F
Y
Q
L
G
D
E
A
M
Site 19
Y242
Q
V
W
L
I
F
E
Y
P
E
S
S
G
S
A
Site 20
S245
L
I
F
E
Y
P
E
S
S
G
S
A
R
A
I
Site 21
S248
E
Y
P
E
S
S
G
S
A
R
A
I
A
I
V
Site 22
S301
P
A
P
G
A
N
G
S
G
V
M
A
P
P
S
Site 23
S348
V
R
F
F
A
C
P
S
K
A
G
F
S
R
N
Site 24
S414
V
F
R
I
F
K
L
S
R
H
S
K
G
L
Q
Site 25
S417
I
F
K
L
S
R
H
S
K
G
L
Q
I
L
G
Site 26
T426
G
L
Q
I
L
G
K
T
L
Q
A
S
M
R
E
Site 27
S498
V
G
G
K
I
V
G
S
L
C
A
I
A
G
V
Site 28
Y521
V
I
V
S
N
F
N
Y
F
Y
H
R
E
T
D
Site 29
Y523
V
S
N
F
N
Y
F
Y
H
R
E
T
D
H
E
Site 30
T541
V
L
K
E
E
Q
G
T
Q
S
Q
G
P
G
L
Site 31
S543
K
E
E
Q
G
T
Q
S
Q
G
P
G
L
D
R
Site 32
S557
R
G
V
Q
R
K
V
S
G
S
R
G
S
F
C
Site 33
S559
V
Q
R
K
V
S
G
S
R
G
S
F
C
K
A
Site 34
S562
K
V
S
G
S
R
G
S
F
C
K
A
G
G
T
Site 35
S575
G
T
L
E
N
A
D
S
A
R
R
G
S
C
P
Site 36
S580
A
D
S
A
R
R
G
S
C
P
L
E
K
C
N
Site 37
S592
K
C
N
V
K
A
K
S
N
V
D
L
R
R
S
Site 38
S599
S
N
V
D
L
R
R
S
L
Y
A
L
C
L
D
Site 39
T607
L
Y
A
L
C
L
D
T
S
R
E
T
D
L
_
Site 40
S608
Y
A
L
C
L
D
T
S
R
E
T
D
L
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation