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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FDXR
Full Name:
NADPH:adrenodoxin oxidoreductase, mitochondrial
Alias:
Adrenodoxin reductase
Type:
Mass (Da):
53819
Number AA:
491
UniProt ID:
P22570
International Prot ID:
IPI00221118
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005739
GO:0005743
GO:0005759
Uniprot
OncoNet
Molecular Function:
GO:0003824
GO:0004324
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006066
GO:0006091
GO:0006118
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T17
G
W
S
A
W
P
R
T
R
L
P
P
A
G
S
Site 2
S24
T
R
L
P
P
A
G
S
T
P
S
F
C
H
H
Site 3
T25
R
L
P
P
A
G
S
T
P
S
F
C
H
H
F
Site 4
S27
P
P
A
G
S
T
P
S
F
C
H
H
F
S
T
Site 5
T34
S
F
C
H
H
F
S
T
Q
E
K
T
P
Q
I
Site 6
T38
H
F
S
T
Q
E
K
T
P
Q
I
C
V
V
G
Site 7
Y52
G
S
G
P
A
G
F
Y
T
A
Q
H
L
L
K
Site 8
T53
S
G
P
A
G
F
Y
T
A
Q
H
L
L
K
H
Site 9
Y68
P
Q
A
H
V
D
I
Y
E
K
Q
P
V
P
F
Site 10
T95
E
V
K
N
V
I
N
T
F
T
Q
T
A
H
S
Site 11
T118
V
E
V
G
R
D
V
T
V
P
E
L
R
E
A
Site 12
S132
A
Y
H
A
V
V
L
S
Y
G
A
E
D
H
R
Site 13
T197
D
V
A
R
I
L
L
T
P
P
E
H
L
E
R
Site 14
T208
H
L
E
R
T
D
I
T
K
A
A
L
G
V
L
Site 15
T222
L
R
Q
S
R
V
K
T
V
W
L
V
G
R
R
Site 16
T277
P
R
P
R
K
R
L
T
E
L
L
L
R
T
A
Site 17
T285
E
L
L
L
R
T
A
T
E
K
P
G
P
A
E
Site 18
S298
A
E
A
A
R
Q
A
S
A
S
R
A
W
G
L
Site 19
S300
A
A
R
Q
A
S
A
S
R
A
W
G
L
R
F
Site 20
S310
W
G
L
R
F
F
R
S
P
Q
Q
V
L
P
S
Site 21
S317
S
P
Q
Q
V
L
P
S
P
D
G
R
R
A
A
Site 22
Y362
L
V
L
S
S
I
G
Y
K
S
R
P
V
D
P
Site 23
S364
L
S
S
I
G
Y
K
S
R
P
V
D
P
S
V
Site 24
S370
K
S
R
P
V
D
P
S
V
P
F
D
S
K
L
Site 25
S375
D
P
S
V
P
F
D
S
K
L
G
V
I
P
N
Site 26
S396
D
V
P
G
L
Y
C
S
G
W
V
K
R
G
P
Site 27
S432
L
K
A
G
L
L
P
S
G
P
R
P
G
Y
A
Site 28
S454
S
R
G
V
R
P
V
S
F
S
D
W
E
K
L
Site 29
S456
G
V
R
P
V
S
F
S
D
W
E
K
L
D
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation