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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CPN2
Full Name:
Carboxypeptidase N subunit 2
Alias:
Carboxypeptidase N 83 kDa chain;Carboxypeptidase N large subunit;Carboxypeptidase N polypeptide 2;Carboxypeptidase N regulatory subunit
Type:
Mass (Da):
60615
Number AA:
545
UniProt ID:
P22792
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T42
C
S
D
E
E
L
A
T
V
P
L
D
I
P
P
Site 2
S71
L
E
T
R
A
F
G
S
N
P
N
L
T
K
V
Site 3
T76
F
G
S
N
P
N
L
T
K
V
V
F
L
N
T
Site 4
T105
R
L
E
D
L
E
V
T
G
S
S
F
L
N
L
Site 5
S107
E
D
L
E
V
T
G
S
S
F
L
N
L
S
T
Site 6
S108
D
L
E
V
T
G
S
S
F
L
N
L
S
T
N
Site 7
S118
N
L
S
T
N
I
F
S
N
L
T
S
L
G
K
Site 8
S149
Q
H
L
A
A
L
E
S
L
H
L
Q
G
N
Q
Site 9
T169
R
R
L
F
Q
P
L
T
H
L
K
T
L
N
L
Site 10
T173
Q
P
L
T
H
L
K
T
L
N
L
A
Q
N
L
Site 11
T193
E
E
L
F
H
P
L
T
S
L
Q
T
L
K
L
Site 12
T197
H
P
L
T
S
L
Q
T
L
K
L
S
N
N
A
Site 13
S201
S
L
Q
T
L
K
L
S
N
N
A
L
S
G
L
Site 14
S206
K
L
S
N
N
A
L
S
G
L
P
Q
G
V
F
Site 15
S226
L
Q
E
L
F
L
D
S
N
N
I
S
E
L
P
Site 16
S230
F
L
D
S
N
N
I
S
E
L
P
P
Q
V
F
Site 17
S238
E
L
P
P
Q
V
F
S
Q
L
F
C
L
E
R
Site 18
T303
L
T
H
N
Q
L
E
T
V
A
E
G
T
F
A
Site 19
S317
A
H
L
S
N
L
R
S
L
M
L
S
Y
N
A
Site 20
S367
L
S
K
L
E
L
L
S
L
S
K
N
Q
L
T
Site 21
S369
K
L
E
L
L
S
L
S
K
N
Q
L
T
T
L
Site 22
T374
S
L
S
K
N
Q
L
T
T
L
P
E
G
I
F
Site 23
T383
L
P
E
G
I
F
D
T
N
Y
N
L
F
N
L
Site 24
Y413
L
F
N
W
L
Q
Q
Y
T
D
R
L
L
N
I
Site 25
T422
D
R
L
L
N
I
Q
T
Y
C
A
G
P
A
Y
Site 26
T457
D
H
L
G
F
Q
V
T
W
P
D
E
S
K
A
Site 27
S479
V
Q
E
R
A
A
R
S
Q
C
T
Y
S
N
P
Site 28
Y483
A
A
R
S
Q
C
T
Y
S
N
P
E
G
T
V
Site 29
S484
A
R
S
Q
C
T
Y
S
N
P
E
G
T
V
V
Site 30
S507
R
W
L
N
V
Q
L
S
P
W
Q
G
S
L
G
Site 31
Y517
Q
G
S
L
G
L
Q
Y
N
A
S
Q
E
W
D
Site 32
S520
L
G
L
Q
Y
N
A
S
Q
E
W
D
L
R
S
Site 33
S527
S
Q
E
W
D
L
R
S
S
C
G
S
L
R
L
Site 34
S528
Q
E
W
D
L
R
S
S
C
G
S
L
R
L
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation