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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AMPD1
Full Name:
AMP deaminase 1
Alias:
AMP deaminase isoform M;Myoadenylate deaminase
Type:
Mass (Da):
86490
Number AA:
747
UniProt ID:
P23109
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S39
E
G
G
R
Q
E
I
S
P
F
D
V
D
E
I
Site 2
T63
A
H
I
F
H
L
E
T
L
S
T
S
T
E
A
Site 3
S65
I
F
H
L
E
T
L
S
T
S
T
E
A
R
R
Site 4
T66
F
H
L
E
T
L
S
T
S
T
E
A
R
R
K
Site 5
T81
K
R
F
Q
G
R
K
T
V
N
L
S
I
P
L
Site 6
S85
G
R
K
T
V
N
L
S
I
P
L
S
E
T
S
Site 7
S89
V
N
L
S
I
P
L
S
E
T
S
S
T
K
L
Site 8
T91
L
S
I
P
L
S
E
T
S
S
T
K
L
S
H
Site 9
S92
S
I
P
L
S
E
T
S
S
T
K
L
S
H
I
Site 10
S93
I
P
L
S
E
T
S
S
T
K
L
S
H
I
D
Site 11
S97
E
T
S
S
T
K
L
S
H
I
D
E
Y
I
S
Site 12
Y102
K
L
S
H
I
D
E
Y
I
S
S
S
P
T
Y
Site 13
S104
S
H
I
D
E
Y
I
S
S
S
P
T
Y
Q
T
Site 14
S105
H
I
D
E
Y
I
S
S
S
P
T
Y
Q
T
V
Site 15
S106
I
D
E
Y
I
S
S
S
P
T
Y
Q
T
V
P
Site 16
T108
E
Y
I
S
S
S
P
T
Y
Q
T
V
P
D
F
Site 17
Y109
Y
I
S
S
S
P
T
Y
Q
T
V
P
D
F
Q
Site 18
T111
S
S
S
P
T
Y
Q
T
V
P
D
F
Q
R
V
Site 19
Y124
R
V
Q
I
T
G
D
Y
A
S
G
V
T
V
E
Site 20
S126
Q
I
T
G
D
Y
A
S
G
V
T
V
E
D
F
Site 21
Y150
A
L
C
I
R
E
K
Y
M
Q
K
S
F
Q
R
Site 22
S154
R
E
K
Y
M
Q
K
S
F
Q
R
F
P
K
T
Site 23
T161
S
F
Q
R
F
P
K
T
P
S
K
Y
L
R
N
Site 24
Y165
F
P
K
T
P
S
K
Y
L
R
N
I
D
G
E
Site 25
T185
E
S
F
Y
P
V
F
T
P
P
V
K
K
G
E
Site 26
Y206
N
L
P
E
N
L
G
Y
H
L
K
M
K
D
G
Site 27
Y216
K
M
K
D
G
V
V
Y
V
Y
P
N
E
A
A
Site 28
Y218
K
D
G
V
V
Y
V
Y
P
N
E
A
A
V
S
Site 29
S225
Y
P
N
E
A
A
V
S
K
D
E
P
K
P
L
Site 30
Y234
D
E
P
K
P
L
P
Y
P
N
L
D
T
F
L
Site 31
T239
L
P
Y
P
N
L
D
T
F
L
D
D
M
N
F
Site 32
Y259
A
Q
G
P
V
K
T
Y
T
H
R
R
L
K
F
Site 33
T260
Q
G
P
V
K
T
Y
T
H
R
R
L
K
F
L
Site 34
S268
H
R
R
L
K
F
L
S
S
K
F
Q
V
H
Q
Site 35
S269
R
R
L
K
F
L
S
S
K
F
Q
V
H
Q
M
Site 36
Y295
N
N
P
H
R
D
F
Y
N
C
R
K
V
D
T
Site 37
S322
L
L
R
F
I
K
K
S
Y
Q
I
D
A
D
R
Site 38
Y332
I
D
A
D
R
V
V
Y
S
T
K
E
K
N
L
Site 39
T334
A
D
R
V
V
Y
S
T
K
E
K
N
L
T
L
Site 40
T340
S
T
K
E
K
N
L
T
L
K
E
L
F
A
K
Site 41
Y353
A
K
L
K
M
H
P
Y
D
L
T
V
D
S
L
Site 42
T356
K
M
H
P
Y
D
L
T
V
D
S
L
D
V
H
Site 43
S359
P
Y
D
L
T
V
D
S
L
D
V
H
A
G
R
Site 44
T368
D
V
H
A
G
R
Q
T
F
Q
R
F
D
K
F
Site 45
Y379
F
D
K
F
N
D
K
Y
N
P
V
G
A
S
E
Site 46
Y391
A
S
E
L
R
D
L
Y
L
K
T
D
N
Y
I
Site 47
T394
L
R
D
L
Y
L
K
T
D
N
Y
I
N
G
E
Site 48
Y397
L
Y
L
K
T
D
N
Y
I
N
G
E
Y
F
A
Site 49
Y402
D
N
Y
I
N
G
E
Y
F
A
T
I
I
K
E
Site 50
Y419
A
D
L
V
E
A
K
Y
Q
H
A
E
P
R
L
Site 51
S427
Q
H
A
E
P
R
L
S
I
Y
G
R
S
P
D
Site 52
Y429
A
E
P
R
L
S
I
Y
G
R
S
P
D
E
W
Site 53
S432
R
L
S
I
Y
G
R
S
P
D
E
W
S
K
L
Site 54
S437
G
R
S
P
D
E
W
S
K
L
S
S
W
F
V
Site 55
Y463
M
I
Q
V
P
R
I
Y
D
V
F
R
S
K
N
Site 56
S500
P
Q
A
D
P
E
L
S
V
F
L
K
H
I
T
Site 57
T507
S
V
F
L
K
H
I
T
G
F
D
S
V
D
D
Site 58
S511
K
H
I
T
G
F
D
S
V
D
D
E
S
K
H
Site 59
S519
V
D
D
E
S
K
H
S
G
H
M
F
S
S
K
Site 60
S525
H
S
G
H
M
F
S
S
K
S
P
K
P
Q
E
Site 61
S527
G
H
M
F
S
S
K
S
P
K
P
Q
E
W
T
Site 62
T534
S
P
K
P
Q
E
W
T
L
E
K
N
P
S
Y
Site 63
Y541
T
L
E
K
N
P
S
Y
T
Y
Y
A
Y
Y
M
Site 64
Y543
E
K
N
P
S
Y
T
Y
Y
A
Y
Y
M
Y
A
Site 65
Y544
K
N
P
S
Y
T
Y
Y
A
Y
Y
M
Y
A
N
Site 66
S557
A
N
I
M
V
L
N
S
L
R
K
E
R
G
M
Site 67
T566
R
K
E
R
G
M
N
T
F
L
F
R
P
H
C
Site 68
T580
C
G
E
A
G
A
L
T
H
L
M
T
A
F
M
Site 69
S601
H
G
L
N
L
K
K
S
P
V
L
Q
Y
L
F
Site 70
S624
M
S
P
L
S
N
N
S
L
F
L
E
Y
A
K
Site 71
S645
L
Q
K
G
L
M
I
S
L
S
T
D
D
P
M
Site 72
S647
K
G
L
M
I
S
L
S
T
D
D
P
M
Q
F
Site 73
T657
D
P
M
Q
F
H
F
T
K
E
P
L
M
E
E
Site 74
S693
S
V
L
Q
C
G
I
S
H
E
E
K
V
K
F
Site 75
Y705
V
K
F
L
G
D
N
Y
L
E
E
G
P
A
G
Site 76
T718
A
G
N
D
I
R
R
T
N
V
A
Q
I
R
M
Site 77
Y734
Y
R
Y
E
T
W
C
Y
E
L
N
L
I
A
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation