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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TCEA1
Full Name:
Transcription elongation factor A protein 1
Alias:
GTF2S; SII; TCE1; TCEA; TF2S; Transcription elongation factor A (SII) 1; Transcription elongation factor S-II protein 1; Transcription elongation factor TFIIS.o
Type:
Transcription factor
Mass (Da):
33970
Number AA:
301
UniProt ID:
P23193
International Prot ID:
IPI00333215
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005654
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0016251
GO:0003711
PhosphoSite+
KinaseNET
Biological Process:
GO:0006354
GO:0006366
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T37
E
L
K
N
I
P
M
T
L
E
L
L
Q
S
T
Site 2
S57
V
N
A
I
R
K
Q
S
T
D
E
E
V
T
S
Site 3
T58
N
A
I
R
K
Q
S
T
D
E
E
V
T
S
L
Site 4
S64
K
K
L
L
D
G
P
S
T
E
K
D
L
D
E
Site 5
S68
E
V
T
S
L
A
K
S
L
I
K
S
W
K
K
Site 6
S72
L
A
K
S
L
I
K
S
W
K
K
L
L
D
G
Site 7
S81
K
K
L
L
D
G
P
S
T
E
K
D
L
D
E
Site 8
T96
K
K
K
E
P
A
I
T
S
Q
N
S
P
E
A
Site 9
S97
K
K
E
P
A
I
T
S
Q
N
S
P
E
A
R
Site 10
S100
P
A
I
T
S
Q
N
S
P
E
A
R
E
E
S
Site 11
S107
S
P
E
A
R
E
E
S
T
S
S
G
N
V
S
Site 12
T108
P
E
A
R
E
E
S
T
S
S
G
N
V
S
N
Site 13
S109
E
A
R
E
E
S
T
S
S
G
N
V
S
N
R
Site 14
S110
A
R
E
E
S
T
S
S
G
N
V
S
N
R
K
Site 15
S114
S
T
S
S
G
N
V
S
N
R
K
D
E
T
N
Site 16
T120
V
S
N
R
K
D
E
T
N
A
R
D
T
Y
V
Site 17
T125
D
E
T
N
A
R
D
T
Y
V
S
S
F
P
R
Site 18
Y126
E
T
N
A
R
D
T
Y
V
S
S
F
P
R
A
Site 19
S128
N
A
R
D
T
Y
V
S
S
F
P
R
A
P
S
Site 20
S129
A
R
D
T
Y
V
S
S
F
P
R
A
P
S
T
Site 21
S135
S
S
F
P
R
A
P
S
T
S
D
S
V
R
L
Site 22
T136
S
F
P
R
A
P
S
T
S
D
S
V
R
L
K
Site 23
S137
F
P
R
A
P
S
T
S
D
S
V
R
L
K
C
Site 24
S139
R
A
P
S
T
S
D
S
V
R
L
K
C
R
E
Site 25
Y158
A
L
R
T
G
D
D
Y
I
A
I
G
A
D
E
Site 26
S170
A
D
E
E
E
L
G
S
Q
I
E
E
A
I
Y
Site 27
Y177
S
Q
I
E
E
A
I
Y
Q
E
I
R
N
T
D
Site 28
Y187
I
R
N
T
D
M
K
Y
K
N
R
V
R
S
R
Site 29
S193
K
Y
K
N
R
V
R
S
R
I
S
N
L
K
D
Site 30
S196
N
R
V
R
S
R
I
S
N
L
K
D
A
K
N
Site 31
T224
P
D
L
F
A
R
M
T
A
E
E
M
A
S
D
Site 32
S230
M
T
A
E
E
M
A
S
D
E
L
K
E
M
R
Site 33
T274
K
K
K
N
C
T
Y
T
Q
V
Q
T
R
S
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation