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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ITGA6
Full Name:
Integrin alpha-6
Alias:
CD49f; Integrin alpha-6; Integrin, alpha 6; ITA6; VLA-6
Type:
Receptor, misc.; Adhesion
Mass (Da):
126633
Number AA:
1130
UniProt ID:
P23229
International Prot ID:
IPI00216221
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0004872
PhosphoSite+
KinaseNET
Biological Process:
GO:0007044
GO:0007229
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
Q
L
C
L
L
Y
L
S
A
G
L
L
S
R
L
Site 2
S85
N
R
T
G
G
L
Y
S
C
D
I
T
A
R
G
Site 3
T89
G
L
Y
S
C
D
I
T
A
R
G
P
C
T
R
Site 4
S187
R
G
H
E
K
F
G
S
C
Q
Q
G
V
A
A
Site 5
S317
K
D
E
I
T
F
V
S
G
A
P
R
A
N
H
Site 6
Y449
D
L
G
K
V
F
I
Y
H
G
S
A
N
G
I
Site 7
Y470
V
L
K
G
I
S
P
Y
F
G
Y
S
I
A
G
Site 8
Y473
G
I
S
P
Y
F
G
Y
S
I
A
G
N
M
D
Site 9
S485
N
M
D
L
D
R
N
S
Y
P
D
V
A
V
G
Site 10
T499
G
S
L
S
D
S
V
T
I
F
R
S
R
P
V
Site 11
T512
P
V
I
N
I
Q
K
T
I
T
V
T
P
N
R
Site 12
T560
P
S
I
S
I
V
G
T
L
E
A
E
K
E
R
Site 13
T588
Q
G
S
E
P
K
Y
T
Q
E
L
T
L
K
R
Site 14
T592
P
K
Y
T
Q
E
L
T
L
K
R
Q
K
Q
K
Site 15
S624
R
P
I
P
I
T
A
S
V
E
I
Q
E
P
S
Site 16
S632
V
E
I
Q
E
P
S
S
R
R
R
V
N
S
L
Site 17
S648
E
V
L
P
I
L
N
S
D
E
P
K
T
A
H
Site 18
T716
K
D
I
A
L
E
I
T
V
T
N
S
P
S
N
Site 19
S722
I
T
V
T
N
S
P
S
N
P
R
N
P
T
K
Site 20
T825
Q
D
N
L
A
P
I
T
A
K
A
K
V
V
I
Site 21
T887
K
P
L
T
N
L
G
T
A
T
L
N
I
Q
W
Site 22
T889
L
T
N
L
G
T
A
T
L
N
I
Q
W
P
K
Site 23
S899
I
Q
W
P
K
E
I
S
N
G
K
W
L
L
Y
Site 24
T932
E
I
N
S
L
N
L
T
E
S
H
N
S
R
K
Site 25
S934
N
S
L
N
L
T
E
S
H
N
S
R
K
K
R
Site 26
S937
N
L
T
E
S
H
N
S
R
K
K
R
E
I
T
Site 27
S1043
V
R
V
T
V
F
P
S
K
T
V
A
Q
Y
S
Site 28
T1045
V
T
V
F
P
S
K
T
V
A
Q
Y
S
G
V
Site 29
Y1086
G
F
F
K
R
S
R
Y
D
D
S
V
P
R
Y
Site 30
S1089
K
R
S
R
Y
D
D
S
V
P
R
Y
H
A
V
Site 31
Y1093
Y
D
D
S
V
P
R
Y
H
A
V
R
I
R
K
Site 32
Y1110
R
E
I
K
D
E
K
Y
I
D
N
L
E
K
K
Site 33
Y1129
K
W
N
R
N
E
S
Y
S
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation