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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LOR
Full Name:
Loricrin
Alias:
Type:
Mass (Da):
25761
Number AA:
312
UniProt ID:
P23490
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y3
_
_
_
_
_
M
S
Y
Q
K
K
Q
P
T
P
Site 2
T9
S
Y
Q
K
K
Q
P
T
P
Q
P
P
V
D
C
Site 3
T19
P
P
V
D
C
V
K
T
S
G
G
G
G
G
G
Site 4
S20
P
V
D
C
V
K
T
S
G
G
G
G
G
G
G
Site 5
S29
G
G
G
G
G
G
G
S
G
G
G
G
C
G
F
Site 6
S42
G
F
F
G
G
G
G
S
G
G
G
S
S
G
S
Site 7
S46
G
G
G
S
G
G
G
S
S
G
S
G
C
G
Y
Site 8
S47
G
G
S
G
G
G
S
S
G
S
G
C
G
Y
S
Site 9
S49
S
G
G
G
S
S
G
S
G
C
G
Y
S
G
G
Site 10
Y53
S
S
G
S
G
C
G
Y
S
G
G
G
G
Y
S
Site 11
S54
S
G
S
G
C
G
Y
S
G
G
G
G
Y
S
G
Site 12
S60
Y
S
G
G
G
G
Y
S
G
G
G
C
G
G
G
Site 13
S68
G
G
G
C
G
G
G
S
S
G
G
G
G
G
G
Site 14
S69
G
G
C
G
G
G
S
S
G
G
G
G
G
G
G
Site 15
S84
I
G
G
C
G
G
G
S
G
G
S
V
K
Y
S
Site 16
S87
C
G
G
G
S
G
G
S
V
K
Y
S
G
G
G
Site 17
Y90
G
S
G
G
S
V
K
Y
S
G
G
G
G
S
S
Site 18
S91
S
G
G
S
V
K
Y
S
G
G
G
G
S
S
G
Site 19
S96
K
Y
S
G
G
G
G
S
S
G
G
G
S
G
C
Site 20
S97
Y
S
G
G
G
G
S
S
G
G
G
S
G
C
F
Site 21
S101
G
G
S
S
G
G
G
S
G
C
F
S
S
G
G
Site 22
S105
G
G
G
S
G
C
F
S
S
G
G
G
G
S
G
Site 23
S106
G
G
S
G
C
F
S
S
G
G
G
G
S
G
C
Site 24
S111
F
S
S
G
G
G
G
S
G
C
F
S
S
G
G
Site 25
S115
G
G
G
S
G
C
F
S
S
G
G
G
G
S
S
Site 26
S116
G
G
S
G
C
F
S
S
G
G
G
G
S
S
G
Site 27
S121
F
S
S
G
G
G
G
S
S
G
G
G
S
G
C
Site 28
S122
S
S
G
G
G
G
S
S
G
G
G
S
G
C
F
Site 29
S145
G
G
G
S
G
C
F
S
S
G
G
G
G
F
S
Site 30
S146
G
G
S
G
C
F
S
S
G
G
G
G
F
S
G
Site 31
S152
S
S
G
G
G
G
F
S
G
Q
A
V
Q
C
Q
Site 32
S160
G
Q
A
V
Q
C
Q
S
Y
G
G
V
S
S
G
Site 33
Y161
Q
A
V
Q
C
Q
S
Y
G
G
V
S
S
G
G
Site 34
S165
C
Q
S
Y
G
G
V
S
S
G
G
S
S
G
G
Site 35
S166
Q
S
Y
G
G
V
S
S
G
G
S
S
G
G
G
Site 36
S169
G
G
V
S
S
G
G
S
S
G
G
G
S
G
C
Site 37
S170
G
V
S
S
G
G
S
S
G
G
G
S
G
C
F
Site 38
S178
G
G
G
S
G
C
F
S
S
G
G
G
G
G
S
Site 39
S179
G
G
S
G
C
F
S
S
G
G
G
G
G
S
V
Site 40
S185
S
S
G
G
G
G
G
S
V
C
G
Y
S
G
G
Site 41
Y189
G
G
G
S
V
C
G
Y
S
G
G
G
S
G
C
Site 42
S190
G
G
S
V
C
G
Y
S
G
G
G
S
G
C
G
Site 43
S194
C
G
Y
S
G
G
G
S
G
C
G
G
G
S
S
Site 44
S200
G
S
G
C
G
G
G
S
S
G
G
S
G
S
G
Site 45
S201
S
G
C
G
G
G
S
S
G
G
S
G
S
G
Y
Site 46
S204
G
G
G
S
S
G
G
S
G
S
G
Y
V
S
S
Site 47
S206
G
S
S
G
G
S
G
S
G
Y
V
S
S
Q
Q
Site 48
Y208
S
G
G
S
G
S
G
Y
V
S
S
Q
Q
V
T
Site 49
S210
G
S
G
S
G
Y
V
S
S
Q
Q
V
T
Q
T
Site 50
S211
S
G
S
G
Y
V
S
S
Q
Q
V
T
Q
T
S
Site 51
T215
Y
V
S
S
Q
Q
V
T
Q
T
S
C
A
P
Q
Site 52
S218
S
Q
Q
V
T
Q
T
S
C
A
P
Q
P
S
Y
Site 53
S224
T
S
C
A
P
Q
P
S
Y
G
G
G
S
S
G
Site 54
Y225
S
C
A
P
Q
P
S
Y
G
G
G
S
S
G
G
Site 55
S229
Q
P
S
Y
G
G
G
S
S
G
G
G
G
S
G
Site 56
S230
P
S
Y
G
G
G
S
S
G
G
G
G
S
G
G
Site 57
S235
G
S
S
G
G
G
G
S
G
G
S
G
C
F
S
Site 58
S238
G
G
G
G
S
G
G
S
G
C
F
S
S
G
G
Site 59
S242
S
G
G
S
G
C
F
S
S
G
G
G
G
G
S
Site 60
S243
G
G
S
G
C
F
S
S
G
G
G
G
G
S
S
Site 61
S249
S
S
G
G
G
G
G
S
S
G
C
G
G
G
S
Site 62
S250
S
G
G
G
G
G
S
S
G
C
G
G
G
S
S
Site 63
S256
S
S
G
C
G
G
G
S
S
G
I
G
S
G
C
Site 64
S276
G
S
V
C
G
G
G
S
S
G
G
G
G
G
G
Site 65
S277
S
V
C
G
G
G
S
S
G
G
G
G
G
G
S
Site 66
S284
S
G
G
G
G
G
G
S
S
V
G
G
S
G
S
Site 67
S285
G
G
G
G
G
G
S
S
V
G
G
S
G
S
G
Site 68
S289
G
G
S
S
V
G
G
S
G
S
G
K
G
V
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation